DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment zetaTry and f12

DIOPT Version :9

Sequence 1:	NP_523691.1	Gene:	zetaTry / 36216	FlyBaseID:	FBgn0011556	Length:	280	Species:	Drosophila melanogaster
Sequence 2:	XP_017947702.2	Gene:	f12 / 100493769	XenbaseID:	XB-GENE-1004811	Length:	597	Species:	Xenopus tropicalis

Alignment Length:	258	Identity:	93/258 - (36%)
Similarity:	118/258 - (45%)	Gaps:	41/258 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 RIVGGYATDIAQVPYQISLRYKGITTPENPFRHRCGGSIFNETTIVTAAHCV--------IGTVA 94
            |||||.....|..||..:|...         .|.||||:.:...|||||||:        |..|.
Frog   358 RIVGGLVALPASHPYIAALYID---------NHFCGGSLISPCWIVTAAHCLDQRPNVTKISVVL 413

  Fly    95 SQYKVVAGTNFQTGSDGVIT-NVKEIVMHEGYYSGAAYNNDIAILFVDP--PLPLNNFTIKAIKL 156
            .|      :.|.|.....:| .|::.::||.|| |....:|||::.|..  .|..:.|:.....:
Frog   414 GQ------SRFNTTDQHTVTLLVEKYILHEKYY-GDTLQHDIALVKVKSINGLCASEFSQFVQPI 471

  Fly   157 ALEQPIEGTVSK----VSGWGTTSPGG-YSSNQLLAVDVPIVSNELCDQDYEDFGDETYRITSAM 216
            .|.|..:...|.    |:|||....|. :.:..|....:||:....| |.....||   |:...|
Frog   472 CLPQQFKMAESTKQCVVAGWGHQYEGAEHYAFFLQEASMPIIPYTQC-QSPSVHGD---RMLPGM 532

  Fly   217 LCAGKRGVGGADACQGDSGGPLAV----RDELYGVVSWGNSCALPNYPGVYANVAYLRPWIDA 275
            ||||.. .||.|||||||||||..    |.||:||||||:.||..|.||||..|.....||.|
Frog   533 LCAGFM-EGGVDACQGDSGGPLVCEVDGRIELHGVVSWGSGCAEENKPGVYTAVTSYTDWIRA 594

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zetaTry	NP_523691.1	Tryp_SPc	38..273	CDD:214473	90/254 (35%)
zetaTry	NP_523691.1	Tryp_SPc	39..276	CDD:238113	92/257 (36%)
f12	XP_017947702.2	fn2	46..87	CDD:394995
		EGF_CA	95..129	CDD:238011
		KR	213..298	CDD:214527
		Tryp_SPc	359..595	CDD:238113	92/257 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910