DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment zetaTry and tmprss3

DIOPT Version :9

Sequence 1:	NP_523691.1	Gene:	zetaTry / 36216	FlyBaseID:	FBgn0011556	Length:	280	Species:	Drosophila melanogaster
Sequence 2:	XP_031752328.1	Gene:	tmprss3 / 100490444	XenbaseID:	XB-GENE-994580	Length:	483	Species:	Xenopus tropicalis

Alignment Length:	244	Identity:	93/244 - (38%)
Similarity:	126/244 - (51%)	Gaps:	23/244 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 RIVGGYATDIAQVPYQISLRYKGITTPENPFRHRCGGSIFNETTIVTAAHCVIGTVASQ-YKVVA 101
            |||||..:.:.|.|:|.||.::|:        |.||||:.....||||||||...:..: ::|..
Frog   243 RIVGGNVSAVGQWPWQASLVFQGV--------HLCGGSLITPQWIVTAAHCVYDLLYPEWWRVQV 299

  Fly   102 GTNFQTG-SDGVITNVKEIVMHEGYYSGAAYNNDIAILFVDPPLPLNNFTIKAIKLA--LEQPIE 163
            |...|.. |......|::|:.|..|.| :...||||::.:..|...|. :|:.|.|.  .|...|
Frog   300 GQVSQASESAQTAVPVQKIIYHSKYRS-STMANDIALIRLASPFTFNG-SIQPICLPNYREDFPE 362

  Fly   164 GTVSKVSGWGTTSPGGYSSNQLLAVDVPIVSNELCDQDYEDFGDETYRITSAMLCAGKRGVGGAD 228
            |.:..:||||.|..||.:|..:....||::||.:|:..|...|    .|..:|:|||.. .||.|
Frog   363 GKICWISGWGATEEGGDTSQTMDYAGVPLISNRVCNTKYIYGG----VIKPSMVCAGFL-EGGVD 422

  Fly   229 ACQGDSGGPLAVRD----ELYGVVSWGNSCALPNYPGVYANVAYLRPWI 273
            .||||||||||..|    :|.|..|||..|||...||||..::....||
Frog   423 TCQGDSGGPLACEDSNVWKLMGTTSWGIGCALRYKPGVYTRISSFLDWI 471

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zetaTry	NP_523691.1	Tryp_SPc	38..273	CDD:214473	91/242 (38%)
zetaTry	NP_523691.1	Tryp_SPc	39..276	CDD:238113	92/243 (38%)
tmprss3	XP_031752328.1	LDLa	96..128	CDD:197566
		SRCR_2	136..236	CDD:406055
		Tryp_SPc	244..472	CDD:238113	92/243 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910