DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment zetaTry and klkb1

DIOPT Version :9

Sequence 1:	NP_523691.1	Gene:	zetaTry / 36216	FlyBaseID:	FBgn0011556	Length:	280	Species:	Drosophila melanogaster
Sequence 2:	XP_002934450.3	Gene:	klkb1 / 100486524	XenbaseID:	XB-GENE-985051	Length:	629	Species:	Xenopus tropicalis

Alignment Length:	260	Identity:	92/260 - (35%)
Similarity:	128/260 - (49%)	Gaps:	50/260 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 RIVGGYATDIAQVPYQISLR------YKGITTPENPFRHRCGGSIFNETTIVTAAHC-------- 88
            |||||..:.:.:.|:|:|:.      ||         :|.|||||.:...|||||||
Frog   390 RIVGGTDSVLGEWPWQVSMHLRLTASYK---------KHACGGSIISNQWIVTAAHCFAMHPLPQ 445

  Fly    89 ---VIGTVASQYKVVAGTNFQTGSDGVITNVKEIVMHEGYYSGAAYNNDIAILFVDPPLPLNNFT 150
               :...|.....:...|.|        :..::|::|. :|:||....|||:|.:..|:..|:..
Frog   446 MWIIYSGVVKLSNITQSTPF--------SETEQIIIHP-HYTGAGNGTDIALLKLKTPISFNDHQ 501

  Fly   151 IKAIKLALEQP--IEGTVSKVSGWGTTSPGGYSSNQLLAVDVPIVSNELCDQDYEDFGDETYRIT 213
             |||.|...:|  :......::|||.|...|..:|.|...:||.:|.|.|..:||.     .||.
Frog   502 -KAICLPPREPTFVLPNSCWITGWGFTEESGSLANILQKAEVPQISTEECQGNYEQ-----TRID 560

  Fly   214 SAMLCAG-KRGVGGADACQGDSGGPLA-VRDELY---GVVSWGNSCALPNYPGVYANVAYLRPWI 273
            ..:|||| ||  |..|:|:|||||||| |.||::   |:.|||..||.|..||||..|:....||
Frog   561 KKILCAGYKR--GKIDSCKGDSGGPLACVVDEIWYLTGITSWGEGCARPGKPGVYTRVSEFTDWI 623

Fly 274 273
Frog 624 623

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zetaTry	NP_523691.1	Tryp_SPc	38..273	CDD:214473	90/258 (35%)
zetaTry	NP_523691.1	Tryp_SPc	39..276	CDD:238113	91/259 (35%)
klkb1	XP_002934450.3	APPLE	21..103	CDD:128519
		APPLE	110..193	CDD:128519
		APPLE	200..283	CDD:128519
		APPLE	290..373	CDD:128519
		Tryp_SPc	391..626	CDD:238113	91/259 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910