DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment zetaTry and tmprss15

DIOPT Version :9

Sequence 1:	NP_523691.1	Gene:	zetaTry / 36216	FlyBaseID:	FBgn0011556	Length:	280	Species:	Drosophila melanogaster
Sequence 2:	XP_001919639.2	Gene:	tmprss15 / 100148042	ZFINID:	ZDB-GENE-091204-83	Length:	990	Species:	Danio rerio

Alignment Length:	268	Identity:	81/268 - (30%)
Similarity:	126/268 - (47%)	Gaps:	45/268 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 LLEDLDEKSVPDGRIVGGYATDIAQVPYQISLRYKGITTPENPFRHRCGGSIFNETTIVTAAHCV 89
            ::|:.|.|.  :||:|||........|:.:||::.|        .|.||.::.:...::||||||
Zfish   736 IIEETDGKK--EGRVVGGQDAQRGAWPWMVSLQWLG--------GHACGATLIDREWLITAAHCV 790

  Fly    90 IG--TVASQYKVVAG--TNFQT-GSDGVITNVKEIVMHEGYYSGAAYNNDIAILFVDPPLPLNNF 149
            .|  ...|.:..|.|  ..|:| ..:..:.:|.:::||: :|:.....:|.|::.:..|:...::
Zfish   791 YGRNVQLSNWAAVLGLHAQFETINPNKQVFSVDQVIMHK-HYNKRTKESDFALMHLKTPVSYTDY 854

  Fly   150 TIKAIKLALEQPI----------EGTVSKVSGWGTTSPGGYSSNQLLAVDVPIVSNELCDQDYED 204
            .         |||          ||....::|||..|..|..::.|....||::||..|.:...:
Zfish   855 V---------QPICLPDPGAHFEEGRKCFIAGWGLLSESGLKADVLQQAVVPLLSNTQCQEWLPE 910

  Fly   205 FGDETYRITSAMLCAGKRGVGGADACQGDSGGPLAVRDE----LYGVVSWGNSCALPNYPGVYAN 265
                 |..|..|:||| ...||.|.|||||||||...:|    |.|..|:|..|..|..||.||.
Zfish   911 -----YNFTERMMCAG-YAEGGVDTCQGDSGGPLMCEEEGHWVLVGATSFGIGCGRPQRPGAYAR 969

  Fly   266 VAYLRPWI 273
            |:....|:
Zfish   970 VSQFVDWV 977

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zetaTry	NP_523691.1	Tryp_SPc	38..273	CDD:214473	76/253 (30%)
zetaTry	NP_523691.1	Tryp_SPc	39..276	CDD:238113	76/254 (30%)
tmprss15	XP_001919639.2	SEA	19..>89	CDD:279699
		LDLa	142..175	CDD:238060
		CUB	183..288	CDD:238001
		MAM	302..457	CDD:279023
		MAM	302..457	CDD:99706
		CUB	477..586	CDD:238001
		LDLa	596..630	CDD:238060
		SRCR_2	653..728	CDD:295335
		Tryp_SPc	747..977	CDD:214473	76/253 (30%)
		Tryp_SPc	748..980	CDD:238113	76/254 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910