DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment zetaTry and tmprss3a

DIOPT Version :9

Sequence 1:	NP_523691.1	Gene:	zetaTry / 36216	FlyBaseID:	FBgn0011556	Length:	280	Species:	Drosophila melanogaster
Sequence 2:	XP_021334565.1	Gene:	tmprss3a / 100000148	ZFINID:	ZDB-GENE-070912-70	Length:	543	Species:	Danio rerio

Alignment Length:	244	Identity:	89/244 - (36%)
Similarity:	122/244 - (50%)	Gaps:	24/244 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 RIVGGYATDIAQVPYQISLRYKGITTPENPFRHRCGGSIFNETTIVTAAHCVIGTVASQYKVVAG 102
            |||||..:...|.|:|:||.::.        .|.|||||.....|:||||||.|.....|.:|..
Zfish   297 RIVGGNLSAEGQFPWQVSLHFQN--------EHLCGGSIITSRWILTAAHCVYGIAYPMYWMVYA 353

  Fly   103 TNFQTGSDGVITNVKEIVMHEGYYSGAAYNNDIAILFVDPPLPLNNFTIKAIKLAL--EQPIEGT 165
            ...:...:.|.....|.:::...|.....::|||::.:..||..|.. ::.|.|..  ||..:|.
Zfish   354 GLTELPLNAVKAFAVEKIIYHSRYRPKGLDHDIALMKLAQPLTFNGM-VEPICLPNFGEQFEDGK 417

  Fly   166 VSKVSGWGTTSPGGYSSNQLLAVDVPIVSNELCDQDYEDFGDETYR--ITSAMLCAGKRGVGGAD 228
            :..:||||.|..||.:|.......||::||:.|.|      .|.|:  :|:.|:|||... ||.|
Zfish   418 MCWISGWGATEDGGDASVSQHCASVPLISNKACSQ------PEVYQGYLTAGMICAGYLD-GGTD 475

  Fly   229 ACQGDSGGPLAVRD----ELYGVVSWGNSCALPNYPGVYANVAYLRPWI 273
            :||||||||||..|    :|.|..|||..||..|.||||..:.....||
Zfish   476 SCQGDSGGPLACEDSSIWKLVGATSWGQGCAEKNKPGVYTRITQSLTWI 524

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zetaTry	NP_523691.1	Tryp_SPc	38..273	CDD:214473	87/242 (36%)
zetaTry	NP_523691.1	Tryp_SPc	39..276	CDD:238113	88/243 (36%)
tmprss3a	XP_021334565.1	LDLa	154..186	CDD:238060
		SRCR_2	191..292	CDD:317845
		Tryp_SPc	298..525	CDD:238113	88/243 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910