Protein Alignment kappaTry and KLK4

DIOPT Version :10

• Sequence 1: NP_610674.5
• Gene: kappaTry / 36215
• FlyBaseID: FBgn0043471
• Length: 263
• Species: Drosophila melanogaster
• Sequence 2: NP_004908.4
• Gene: KLK4 / 9622
• HGNCID: 6365
• Length: 254
• Species: Homo sapiens
• Alignment Length: 272
• Identity: 81/272 - (29%)
• Similarity: 122/272 - (44%)
• Gaps: 49/272 - (18%)

  Fly     6 LLLAIGFSSVISISGQPEGRIINGTTVDIARHPYLVSLRYRRDNESSYMHECAGVIISEQALITS 70
            |:|.:..|.|.....|    ||||........|:..:|  ..:||..    |:||::..|.::::
Human    15 LILGVAGSLVSGSCSQ----IINGEDCSPHSQPWQAAL--VMENELF----CSGVLVHPQWVLSA 69

  Fly    71 AQC----------LYGL---PEETKLVAVAGANTRNGTDGFIYPVANWTHHPNYDPVTVDNDIGV 122
            |.|          |:.|   .|....:..|..:.|               ||.|:...:.||:.:
Human    70 AHCFQNSYTIGLGLHSLEADQEPGSQMVEASLSVR---------------HPEYNRPLLANDLML 119

  Fly   123 LLLDTTLDLTLLGISSIGIRPERPAVGRLATVAGWGYREEWGPSSYKLEQTEVPVVSSEQCTQIY 187
            :.||.::..:.. |.||.|..:.|..|....|:|||.... |.....|:...|.|||.|.|:::|
Human   120 IKLDESVSESDT-IRSISIASQCPTAGNSCLVSGWGLLAN-GRMPTVLQCVNVSVVSEEVCSKLY 182

  Fly   188 GAGEVTERMICAGFVVQGG---SDACQGDTGGPLVIDGQLVGLVSWGRG-CARPNYPTVYCYVAS 248
            .. .....|.|||    ||   .|:|.||:||||:.:|.|.||||:|:. |.:...|.||..:..
Human   183 DP-LYHPSMFCAG----GGQDQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCK 242

  Fly   249 FVDWIEETIAAA 260
            |.:|||:|:.|:
Human   243 FTEWIEKTVQAS 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kappaTry	NP_610674.5	Tryp_SPc	26..256	CDD:238113	74/246 (30%)
KLK4	NP_004908.4	Tryp_SPc	31..250	CDD:238113	74/246 (30%)