DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment kappaTry and tmprss7

DIOPT Version :9

Sequence 1:	NP_610674.5	Gene:	kappaTry / 36215	FlyBaseID:	FBgn0043471	Length:	263	Species:	Drosophila melanogaster
Sequence 2:	XP_002666699.2	Gene:	tmprss7 / 798480	ZFINID:	ZDB-GENE-130530-883	Length:	840	Species:	Danio rerio

Alignment Length:	255	Identity:	86/255 - (33%)
Similarity:	121/255 - (47%)	Gaps:	36/255 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 PEGRIINGTTVDIARHPYLVSLRYRRDNESSYMHECAGVIISEQALITSAQCLYG---LPEETKL 83
            |:.||:.|........|:.||:.:     |..:: |...::|:..||::|.| |.   |.:....
Zfish   598 PQQRIVGGVNAVEGEWPWQVSMHF-----SGQLY-CGASVLSDVWLISAAHC-YSKERLADPRMW 655

  Fly    84 VAVAGANTRNGTDGFIYPVANWTHHPNYDPVTVDNDIGVLLLDTTLDLTLLGISSIGIRPE-RPA 147
            :|..|. ...|:...:..:.....|..|:....|.||.:|.|.....   .|:... |:|. .||
Zfish   656 MAHLGM-LNQGSAKHVAEIRRIVVHEYYNARNFDYDIALLQLKKVWP---SGLEQY-IQPVCLPA 715

  Fly   148 VGRLAT------VAGWGYREEWG---PSSYKLEQTEVPVVSSEQCTQIYGAGEVTERMICAGFVV 203
            ..:..|      |.|||||.|..   |:  .|::.||.|:|..:|.:.|  |.|:.||:||| |.
Zfish   716 PSQTFTEGHRCWVTGWGYRSEQDKVLPT--VLQKAEVNVLSQSECKRSY--GPVSPRMLCAG-VP 775

  Fly   204 QGGSDACQGDTGGPLVIDGQ------LVGLVSWGRGCARPNYPTVYCYVASFVDWIEETI 257
            .|..|||:||:||||....|      |.|:||||.||.||..|.||..||.|:|||:..|
Zfish   776 SGEQDACRGDSGGPLSCQAQTGSRWFLTGIVSWGSGCGRPYLPGVYTRVAKFIDWIQRHI 835

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kappaTry	NP_610674.5	Tryp_SPc	25..253	CDD:214473	82/246 (33%)
kappaTry	NP_610674.5	Tryp_SPc	26..256	CDD:238113	83/248 (33%)
tmprss7	XP_002666699.2	SEA	99..203	CDD:307516
		CUB	<260..344	CDD:238001
		CUB	367..465	CDD:294042
		LDLa	472..506	CDD:238060
		LDLa	546..581	CDD:238060
		Tryp_SPc	601..831	CDD:214473	82/246 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010