DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment kappaTry and st14b

DIOPT Version :9

Sequence 1:	NP_610674.5	Gene:	kappaTry / 36215	FlyBaseID:	FBgn0043471	Length:	263	Species:	Drosophila melanogaster
Sequence 2:	XP_005161261.1	Gene:	st14b / 777629	ZFINID:	ZDB-GENE-061103-613	Length:	864	Species:	Danio rerio

Alignment Length:	265	Identity:	87/265 - (32%)
Similarity:	118/265 - (44%)	Gaps:	62/265 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 RIINGTTVDIARHPYLVSLRYRRDNESSYMHECAGVIISEQALITSAQCLYGLPEETKLVAVAGA 89
            ||:.|...|....|:.|||..:...     |.|...:||...|:|:|.|:
Zfish   624 RIVGGKDSDEGEWPWQVSLHMKTQG-----HVCGASVISNSWLVTAAHCV--------------- 668

  Fly    90 NTRNGTDGFIYPVAN-W-----TH------------------HPNYDPVTVDNDIGVLLLDT--T 128
               ...|.|.|..|: |     .|                  ||.||..:.||||.::.||:  |
Zfish   669 ---QDNDQFRYSQADQWEVYLGLHNQGETSKSTQRSVLRIIPHPQYDHSSYDNDIALMELDSPVT 730

  Fly   129 LDLTLLGISSIGIRPERPAVGRLATVAGWGYREEWG---PSSYKLEQTEVPVVSSEQCTQIYGAG 190
            |:..:..|.........|| |:...:.|||...|..   ||  .|::.||.:::|..|:::...|
Zfish   731 LNQNIWPICLPDPTHYFPA-GKSVWITGWGKLREGSDAVPS--VLQKAEVRIINSTVCSKLMDDG 792

  Fly   191 EVTERMICAGFVVQGGSDACQGDTGGPL-VIDGQ----LVGLVSWGRGCARPNYPTVYCYVASFV 250
             :|..||||| |:.||.||||||:|||: .|:|.    |.|:||||.||.|.|.|.||..|..:.
Zfish   793 -ITPHMICAG-VLSGGVDACQGDSGGPMSSIEGNGRMFLAGVVSWGDGCGRRNRPGVYTRVTDYR 855

  Fly   251 DWIEE 255
            .||.|
Zfish   856 SWIRE 860

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kappaTry	NP_610674.5	Tryp_SPc	25..253	CDD:214473	84/261 (32%)
kappaTry	NP_610674.5	Tryp_SPc	26..256	CDD:238113	86/264 (33%)
st14b	XP_005161261.1	SEA	92..180	CDD:279699
		CUB	233..342	CDD:238001
		CUB	351..457	CDD:238001
		LDLa	465..497	CDD:238060
		LDLa	499..533	CDD:238060
		LDLa	536..570	CDD:238060
		LDLa	578..613	CDD:238060
		Tryp_SPc	624..858	CDD:214473	84/261 (32%)
		Tryp_SPc	625..861	CDD:238113	86/264 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920