DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment kappaTry and CG18754

DIOPT Version :9

Sequence 1:	NP_610674.5	Gene:	kappaTry / 36215	FlyBaseID:	FBgn0043471	Length:	263	Species:	Drosophila melanogaster
Sequence 2:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster

Alignment Length:	268	Identity:	65/268 - (24%)
Similarity:	103/268 - (38%)	Gaps:	54/268 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 GQ--PEGRIINGTTVDIARHPYLVSLRYRRDNESSYMHECAGVIISEQALITSAQCLYG--LPEE 80
            ||  |..|.......::..:|::|.|.|  :|..|.:          :.::|:|.|:.|  |.:.
  Fly    98 GQTTPVFRDRGAENAELNEYPWMVLLLY--ENRLSLI----------RYVLTAAHCVIGGYLTQN 150

  Fly    81 ---TKLVAVAGANTRNGTDGFIYP-----VANWTHHPNYDPV--TVDNDIGVLLLDTTLDLTLLG 135
               .|.|.:..:.|...|.....|     |...|.|..:...  |..|||.:|.|...:..|.
  Fly   151 DLVLKSVRLGESTTDCITSESRCPHLDVEVGQTTVHQGFTSSGGTYRNDIALLRLQFPVRYTK-- 213

  Fly   136 ISSIGIRP------ERPAVGRLATVAGWGYREEWGPSSYKLEQTEVPVVSSEQCTQIYGAGEVTE 194
                .|:|      |.|.......::||...:    ||..|..:.|...:...|...|.:.. :.
  Fly   214 ----KIQPICLLDAEFPLQDLNLQISGWDPTK----SSQTLITSTVKERNPADCLNRYPSFR-SA 269

  Fly   195 RMICAGFVVQGGSDACQGDTGGPLV-IDGQ-------LVGLVSWGRG-CARPNYPTVYCYVASFV 250
            ..:|||...:|  |.|.|.:|.|:: |.|.       |.|:.|:|:. |.....|.||..:..|.
  Fly   270 SQVCAGGQRKG--DTCAGISGSPVMGIMGSGVDEFVFLAGIASYGQQYCYSAGIPGVYTKIGHFS 332

  Fly   251 DWIEETIA 258
            :||:..:|
  Fly   333 EWIKANLA 340

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kappaTry	NP_610674.5	Tryp_SPc	25..253	CDD:214473	59/254 (23%)
kappaTry	NP_610674.5	Tryp_SPc	26..256	CDD:238113	60/256 (23%)
CG18754	NP_652652.3	CLIP	35..84	CDD:288855
		Tryp_SPc	108..338	CDD:238113	60/254 (24%)
		Tryp_SPc	108..335	CDD:214473	58/251 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S7758
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.950