Protein Alignment kappaTry and KLK6

DIOPT Version :10

• Sequence 1: NP_610674.5
• Gene: kappaTry / 36215
• FlyBaseID: FBgn0043471
• Length: 263
• Species: Drosophila melanogaster
• Sequence 2: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Alignment Length: 255
• Identity: 75/255 - (29%)
• Similarity: 121/255 - (47%)
• Gaps: 18/255 - (7%)

  Fly     8 LAIGFSSVISISGQPEGRIINGTTVDIARHPYLVSLRYRRDNESSYMHECAGVIISEQALITSAQ 72
            |.:..|.:.:...:.:.::::|...|...|||..:|     ..|.:: .|.||:|....::|:|.
Human     4 LMVVLSLIAAAWAEEQNKLVHGGPCDKTSHPYQAAL-----YTSGHL-LCGGVLIHPLWVLTAAH 62

  Fly    73 CLYGLPEETKLVAVAGANT--RNGTDGFIYPVANWTHHPNYDPVTVDNDIGVLLLDTTLDLTLLG 135
            |     ::..|....|.:.  :..:......|.....||:||..:.|.||.:|.|.....|:.|
Human    63 C-----KKPNLQVFLGKHNLRQRESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSEL- 121

  Fly   136 ISSIGIRPERPAVGRLATVAGWGYREEWGPSSYKLEQTEVPVVSSEQCTQIYGAGEVTERMICAG 200
            |..:.:..:..|......:.|||...: |.....::...:.:||.|:|...| .|::|:.|:|||
Human   122 IQPLPLERDCSANTTSCHILGWGKTAD-GDFPDTIQCAYIHLVSREECEHAY-PGQITQNMLCAG 184

  Fly   201 FVVQGGSDACQGDTGGPLVIDGQLVGLVSWGR-GCARPNYPTVYCYVASFVDWIEETIAA 259
             ..:.|.|:||||:|||||....|.||||||. .|.....|.||..|..:.:||::||.|
Human   185 -DEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQA 243

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kappaTry	NP_610674.5	Tryp_SPc	26..256	CDD:238113	70/232 (30%)
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	68/228 (30%)