Protein Alignment kappaTry and PRSS2

DIOPT Version :10

• Sequence 1: NP_610674.5
• Gene: kappaTry / 36215
• FlyBaseID: FBgn0043471
• Length: 263
• Species: Drosophila melanogaster
• Sequence 2: NP_001290343.1
• Gene: PRSS2 / 5645
• HGNCID: 9483
• Length: 261
• Species: Homo sapiens
• Alignment Length: 270
• Identity: 94/270 - (34%)
• Similarity: 144/270 - (53%)
• Gaps: 28/270 - (10%)

  Fly     5 LLLLAIGFSSVISISGQPEGRIINGTTVDIARHPYLVSLRYRRDNESSYMHECAGVIISEQALIT 69
            |||:....::.::.....:.:|:.|...:....||.|||      .|.| |.|.|.:||||.:::
Human     3 LLLILTFVAAAVAAPFDDDDKIVGGYICEENSVPYQVSL------NSGY-HFCGGSLISEQWVVS 60

  Fly    70 SAQCLYGLPEETKL-----------VAVAGANTR--NGTDGFIYPVANWTHHPNYDPVTVDNDIG 121
            :..| |.....:||           |.:...|..  .|.:.|| ..|....||.|:..|:||||.
Human    61 AGHC-YKSAINSKLSGRGCEYHRIQVRLGEHNIEVLEGNEQFI-NAAKIIRHPKYNSRTLDNDIL 123

  Fly   122 VLLLDTTLDLTLLGISSIGIRPERPAVGRLATVAGWGYREEWGPSSY--KLEQTEVPVVSSEQCT 184
            ::.|.:...:. ..:|:|.:....||.|..:.::|||.....| :.|  :|:..:.||:|..:|.
Human   124 LIKLSSPAVIN-SRVSAISLPTAPPAAGTESLISGWGNTLSSG-ADYPDELQCLDAPVLSQAECE 186

  Fly   185 QIYGAGEVTERMICAGFVVQGGSDACQGDTGGPLVIDGQLVGLVSWGRGCARPNYPTVYCYVASF 249
            ..| .|::|..|.|.|| ::||.|:||||:|||:|.:|:|.|:||||.|||:.|.|.||..|.::
Human   187 ASY-PGKITNNMFCVGF-LEGGKDSCQGDSGGPVVSNGELQGIVSWGYGCAQKNRPGVYTKVYNY 249

  Fly   250 VDWIEETIAA 259
            ||||::||||
Human   250 VDWIKDTIAA 259

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kappaTry	NP_610674.5	Tryp_SPc	26..256	CDD:238113	87/244 (36%)
PRSS2	NP_001290343.1	Tryp_SPc	24..256	CDD:238113	87/244 (36%)