Protein Alignment kappaTry and PRSS1

DIOPT Version :10

• Sequence 1: NP_610674.5
• Gene: kappaTry / 36215
• FlyBaseID: FBgn0043471
• Length: 263
• Species: Drosophila melanogaster
• Sequence 2: NP_002760.1
• Gene: PRSS1 / 5644
• HGNCID: 9475
• Length: 247
• Species: Homo sapiens
• Alignment Length: 261
• Identity: 90/261 - (34%)
• Similarity: 141/261 - (54%)
• Gaps: 23/261 - (8%)

  Fly     4 PLLLLAIGFSSVISISGQPEGRIINGTTVDIARHPYLVSLRYRRDNESSYMHECAGVIISEQALI 68
            |||:|.. .::.::.....:.:|:.|...:....||.|||      .|.| |.|.|.:|:||.::
Human     3 PLLILTF-VAAALAAPFDDDDKIVGGYNCEENSVPYQVSL------NSGY-HFCGGSLINEQWVV 59

  Fly    69 TSAQCLYGLPEETKLVAVAGAN---TRNGTDGFIYPVANWTHHPNYDPVTVDNDIGVLLLDTTLD 130
            ::..|.     ::::....|.:   ...|.:.|| ..|....||.||..|::|||.::.|.:...
Human    60 SAGHCY-----KSRIQVRLGEHNIEVLEGNEQFI-NAAKIIRHPQYDRKTLNNDIMLIKLSSRAV 118

  Fly   131 LTLLGISSIGIRPERPAVGRLATVAGWGYREEWGPSSY--KLEQTEVPVVSSEQCTQIYGAGEVT 193
            :. ..:|:|.:....||.|....::|||.....| :.|  :|:..:.||:|..:|...| .|::|
Human   119 IN-ARVSTISLPTAPPATGTKCLISGWGNTASSG-ADYPDELQCLDAPVLSQAKCEASY-PGKIT 180

  Fly   194 ERMICAGFVVQGGSDACQGDTGGPLVIDGQLVGLVSWGRGCARPNYPTVYCYVASFVDWIEETIA 258
            ..|.|.|| ::||.|:||||:|||:|.:|||.|:||||.|||:.|.|.||..|.::|.||:.|||
Human   181 SNMFCVGF-LEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIKNTIA 244

  Fly   259 A 259
            |
Human   245 A 245

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kappaTry	NP_610674.5	Tryp_SPc	26..256	CDD:238113	82/234 (35%)
PRSS1	NP_002760.1	Tryp_SPc	23..239	CDD:214473	80/232 (34%)