Protein Alignment kappaTry and KLK15

DIOPT Version :10

• Sequence 1: NP_610674.5
• Gene: kappaTry / 36215
• FlyBaseID: FBgn0043471
• Length: 263
• Species: Drosophila melanogaster
• Sequence 2: NP_059979.2
• Gene: KLK15 / 55554
• HGNCID: 20453
• Length: 256
• Species: Homo sapiens
• Alignment Length: 283
• Identity: 79/283 - (27%)
• Similarity: 123/283 - (43%)
• Gaps: 63/283 - (22%)

  Fly     6 LLLAIGFSSVISISGQPEGRIINGTTVDIARHPYLVSLRYRRDNESSYMHECAGVIISEQALITS 70
            |||.:.| .:.|.:.|...:::.|........|:.|:| |.|..     ..|...:||...::::
Human     3 LLLTLSF-LLASTAAQDGDKLLEGDECAPHSQPWQVAL-YERGR-----FNCGASLISPHWVLSA 60

  Fly    71 AQCLYGLPEETKLVAVA----GANTRNG-----TDGFIYPVANWTHHPNYDPVTVDNDIGVLLLD 126
            |.|      :::.:.|.    ....|:|     |...:.|      ||.|:..:..|||.:|.|
Human    61 AHC------QSRFMRVRLGEHNLRKRDGPEQLRTTSRVIP------HPRYEARSHRNDIMLLRL- 112

  Fly   127 TTLDLTLLGISSIGIRPE-RPAV--------GRLATVAGWGY--REEWGPSSYKLEQTEVP---- 176
                     :....:.|: ||||        |....|:|||.  ..|.|.:.....|..:|
Human   113 ---------VQPARLNPQVRPAVLPTRCPHPGEACVVSGWGLVSHNEPGTAGSPRSQVSLPDTLH 168

  Fly   177 -----VVSSEQCTQIYGAGEVTERMICAGFVVQG-GSDACQGDTGGPLVIDGQLVGLVSWGR-GC 234
                 ::|...|.:.| .|.:|..|:|||  .:| |:::|:||:|||||..|.|.|:||||. .|
Human   169 CANISIISDTSCDKSY-PGRLTNTMVCAG--AEGRGAESCEGDSGGPLVCGGILQGIVSWGDVPC 230

  Fly   235 ARPNYPTVYCYVASFVDWIEETI 257
            .....|.||..|..:::||.||:
Human   231 DNTTKPGVYTKVCHYLEWIRETM 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kappaTry	NP_610674.5	Tryp_SPc	26..256	CDD:238113	71/260 (27%)
KLK15	NP_059979.2	Tryp_SPc	25..249	CDD:214473	69/254 (27%)