Protein Alignment kappaTry and Cfd

DIOPT Version :10

• Sequence 1: NP_610674.5
• Gene: kappaTry / 36215
• FlyBaseID: FBgn0043471
• Length: 263
• Species: Drosophila melanogaster
• Sequence 2: NP_001071110.1
• Gene: Cfd / 54249
• RGDID: 2498
• Length: 263
• Species: Rattus norvegicus
• Alignment Length: 253
• Identity: 72/253 - (28%)
• Similarity: 122/253 - (48%)
• Gaps: 34/253 - (13%)

  Fly    21 QPEGRIINGTTVDIARHPYLVSLRYRRDNESSYMHECAGVIISEQALITSAQCLYGLPEETKLVA 85
            ||.|||:.|........||:.|:      :.:..|.|.|.::.||.::::|.|:.|:.::..:..
  Rat    21 QPRGRILGGQEAMAHARPYMASV------QVNGTHVCGGTLVDEQWVLSAAHCMDGVTKDEVVQV 79

  Fly    86 VAGANTRNGTDGF--IYPVANWTHHPNYDPVTVDNDIGVLLLDTTLDLTLLGISSIG--IRP--- 143
            :.||::.:..:.:  :|.|.:...||...|.:|::|:.:..|...        :|:|  :||
  Rat    80 LLGAHSLSSPEPYKHLYDVQSVVLHPGSRPDSVEDDLMLFKLSHN--------ASLGPHVRPLPL 136

  Fly   144 ------ERPAVGRLATVAGWGYREEWGPSSYKLEQTEVPVVSSEQCT-QIYGAGEVTERMICAGF 201
                  .:|  |.|..|||||.....|.....|:|..|.::....|. :.|..|.:|:.|:||
  Rat   137 QREDREVKP--GTLCDVAGWGVVTHAGRRPDVLQQLTVSIMDRNTCNLRTYHDGAITKNMMCA-- 197

  Fly   202 VVQGGSDACQGDTGGPLVIDGQLVGLVSWG-RGCARPNYPTVYCYVASFVDWIEETIA 258
             .....|.|:||:|||||....:..:|:|| |.|.....|.|:..||::|.|||..::
  Rat   198 -ESNRRDTCRGDSGGPLVCGDAVEAVVTWGSRVCGNRRKPGVFTRVATYVPWIENVLS 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kappaTry	NP_610674.5	Tryp_SPc	26..256	CDD:238113	68/244 (28%)
Cfd	NP_001071110.1	Tryp_SPc	26..252	CDD:238113	68/244 (28%)
		Self-inhibitor loop. /evidence=ECO:0000250|UniProtKB:P00746	224..228		2/3 (67%)