DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment kappaTry and prss60.2

DIOPT Version :9

Sequence 1:	NP_610674.5	Gene:	kappaTry / 36215	FlyBaseID:	FBgn0043471	Length:	263	Species:	Drosophila melanogaster
Sequence 2:	NP_001099071.1	Gene:	prss60.2 / 541408	ZFINID:	ZDB-GENE-050320-109	Length:	328	Species:	Danio rerio

Alignment Length:	283	Identity:	94/283 - (33%)
Similarity:	137/283 - (48%)	Gaps:	49/283 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 IPLLLLAIGFSSVISISGQP--EGRIINGTTVDIARHPYLVSLRYRRDNESSYMHECAGVIISEQ 65
            :.||:...|..|.:::.||.  ..||:.|........|:.|||:..|...    |.|.|.:||.:
Zfish     9 LTLLICVKGSLSQLNVCGQAPLNSRIVGGVNAPEGSWPWQVSLQSPRYGG----HFCGGSLISSE 69

  Fly    66 ALITSAQCLYGLPEETKLVAVAGANTRNGTDGFIYPVANWTH-----------HPNYDPVTVDND 119
            .::|:|.||.|: .|:.||...|..|:.|.:         ||           |.:|:..|.|||
Zfish    70 WVLTAAHCLPGV-SESSLVVYLGRRTQQGVN---------THETSRNVAKIIVHSSYNSNTNDND 124

  Fly   120 IGVLLLDTTLDLTLLGISSIGIRPERPA-------VGRLATVAGWGYREEWG---PSSYKLEQTE 174
            |.:|.|.:.:..      :..|||...|       .|..:.:.||| ..:.|   |:...|::|.
Zfish   125 IALLRLSSAVTF------NDYIRPVCLAAQNSVYSAGTSSWITGWG-DVQAGVNLPAPGILQETM 182

  Fly   175 VPVVSSEQCTQIYGAGEVTERMICAGFVVQGGSDACQGDTGGPLVIDGQLV----GLVSWGRGCA 235
            :|||::::|....|:|.||..||||| :.:||.|.||||:|||:|.....|    |:.|||.|||
Zfish   183 IPVVANDRCNAQLGSGTVTNNMICAG-LAKGGKDTCQGDSGGPMVTRLCTVWIQAGITSWGYGCA 246

  Fly   236 RPNYPTVYCYVASFVDWIEETIA 258
            .||.|.||..|:.:..||...|:
Zfish   247 DPNSPGVYTRVSQYQSWISSKIS 269

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kappaTry	NP_610674.5	Tryp_SPc	25..253	CDD:214473	85/252 (34%)
kappaTry	NP_610674.5	Tryp_SPc	26..256	CDD:238113	86/254 (34%)
prss60.2	NP_001099071.1	Tryp_SPc	33..264	CDD:214473	85/252 (34%)
		Tryp_SPc	34..267	CDD:238113	86/254 (34%)
		Somatomedin_B	296..326	CDD:295334
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920