DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment kappaTry and Prss53

DIOPT Version :9

Sequence 1:	NP_610674.5	Gene:	kappaTry / 36215	FlyBaseID:	FBgn0043471	Length:	263	Species:	Drosophila melanogaster
Sequence 2:	XP_006230384.1	Gene:	Prss53 / 499270	RGDID:	1566127	Length:	591	Species:	Rattus norvegicus

Alignment Length:	231	Identity:	60/231 - (25%)
Similarity:	86/231 - (37%)	Gaps:	70/231 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 CAGVIISEQALITSAQCLYGL-------------PEE--TKLVAVAGANTRNGTDGFIYPVANWT 106
            |.|.::||..::|:|.|..|.             |||  .|.:.:.||.|
  Rat   365 CGGALVSEVVVLTAAHCFIGRQTLEEWSVGLGAGPEEWGLKQLILHGAYT--------------- 414

  Fly   107 HHPNYDPVTVDNDIGVLLLDTTLDLTLLGISSIGIRP-------ERPAVGRLATVAGW--GYREE 162
             ||.     ..:|:..|||...:.|      ..|:||       .|...|.    .||  |...|
  Rat   415 -HPE-----GGHDVAFLLLAQPVTL------GPGLRPLCLPYADHRLPDGE----HGWVLGLTRE 463

  Fly   163 WG---PSSYKLEQTEVPVVSSEQCTQIYGAGEVTERMICAGFV---VQGGSDACQGDTGGPLV-- 219
            .|   |.:     ..|.|:....|::.:.|...|...|..|.:   |.|....|:|.:|.|||
  Rat   464 AGINHPHT-----VPVTVLGPMACSRQHAASGSTGVPILPGMICTTVVGEPPHCEGLSGAPLVHE 523

  Fly   220 IDGQ--LVGLVSWGRGCARPNYPTVYCYVASFVDWI 253
            |.|.  |.||.|:|..|.....|.|:..::::.||:
  Rat   524 IRGTWFLAGLHSFGDTCQGSAKPAVFAALSAYEDWV 559

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kappaTry	NP_610674.5	Tryp_SPc	25..253	CDD:214473	59/229 (26%)
kappaTry	NP_610674.5	Tryp_SPc	26..256	CDD:238113	60/231 (26%)
Prss53	XP_006230384.1	Tryp_SPc	45..310	CDD:238113
Prss53	XP_006230384.1	Tryp_SPc	341..561	CDD:238113	60/231 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166343308
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24276
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.040