DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment kappaTry and Prss36

DIOPT Version :9

Sequence 1:	NP_610674.5	Gene:	kappaTry / 36215	FlyBaseID:	FBgn0043471	Length:	263	Species:	Drosophila melanogaster
Sequence 2:	XP_038942639.1	Gene:	Prss36 / 497040	RGDID:	1593186	Length:	874	Species:	Rattus norvegicus

Alignment Length:	281	Identity:	73/281 - (25%)
Similarity:	115/281 - (40%)	Gaps:	76/281 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 QPEGRIINGTTVDIARHPYLVSLRYRRDNESSYMHECAGVIISEQALITSAQCLYGLPEETKLVA 85
            :|..||:.|:.......|:.|||.:...      |.|.|.:|:...::::|.|..
  Rat    54 EPSSRIVGGSDAHPGTWPWQVSLHHGGG------HICGGSLIAPSWVLSAAHCFV---------- 102

  Fly    86 VAGANTRNGTDGFIYPVANWT---------------HHPNYDPVTVDNDIGVLLLDTTLDLTLLG 135
                     |:|.:.|...|:               |..:...:.|.::...:.|..  ||.||.
  Rat   103 ---------TNGTLEPADEWSVLLGVHSQDGPLEGAHMRSVATILVPDNYSRVELGA--DLALLR 156

  Fly   136 ISSIGIRPER--PAV--------------GRLATVAGWGYREEWG--PSSYKLEQTEVPVVSSEQ 182
            ::|    |.:  |:|              |......|||..:|..  |..:.|::.|:.::....
  Rat   157 LAS----PAKLGPSVKPVCLPRASHLFAHGTACWATGWGDVQESDPLPVPWVLQEVELKLLGETA 217

  Fly   183 CTQIY---GAGEVTER----MICAGFVVQGGSDACQGDTGGPLVI-DGQ---LVGLVSWGRGCAR 236
            |..:|   |...:|.:    |:|||: .:|..|.||||:|||||. ||.   |.|:.|:|.||.|
  Rat   218 CQCLYSRPGPFNLTLQLLPGMLCAGY-PEGRRDTCQGDSGGPLVCEDGGRWFLAGITSFGFGCGR 281

  Fly   237 PNYPTVYCYVASFVDWIEETI 257
            .|.|.|:..||.:..||.|.:
  Rat   282 RNRPGVFTAVAHYESWIREHV 302

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kappaTry	NP_610674.5	Tryp_SPc	25..253	CDD:214473	69/271 (25%)
kappaTry	NP_610674.5	Tryp_SPc	26..256	CDD:238113	70/273 (26%)
Prss36	XP_038942639.1	Tryp_SPc	59..301	CDD:238113	70/273 (26%)
		Tryp_SPc	338..532	CDD:419748
		Tryp_SPc	607..802	CDD:419748
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166343280
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24276
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.040