Protein Alignment kappaTry and KLK12

DIOPT Version :9

• Sequence 1: NP_610674.5
• Gene: kappaTry / 36215
• FlyBaseID: FBgn0043471
• Length: 263
• Species: Drosophila melanogaster
• Sequence 2: NP_062544.1
• Gene: KLK12 / 43849
• HGNCID: 6360
• Length: 254
• Species: Homo sapiens
• Alignment Length: 262
• Identity: 74/262 - (28%)
• Similarity: 112/262 - (42%)
• Gaps: 42/262 - (16%)

  Fly     1 MCIPLLLLAIGFSSVISISGQPEGRIINGTTVDIARHPYLVSLRYRRDNESSYMHECAGVIISEQ 65
            :.|.|||..:|.|...:      .:|.|||.......|:.|.|     .|.:.: .|.||:|..:
Human     3 LSIFLLLCVLGLSQAAT------PKIFNGTECGRNSQPWQVGL-----FEGTSL-RCGGVLIDHR 55

  Fly    66 ALITSAQCLYGLPEETKLVAVAGANTRNGTDGFIYPVANWTH----------HPNYDPVTVDNDI 120
            .::|:|.|     ..::.....|.::.:..|        ||.          ||.|...:..::.
Human    56 WVLTAAHC-----SGSRYWVRLGEHSLSQLD--------WTEQIRHSGFSVTHPGYLGASTSHEH 107

  Fly   121 GVLLLDTTLDLTLL-GISSIGIRPERPAVGRLATVAGWGY-REEWGPSSYKLEQTEVPVVSSEQC 183
            .:.||...|.:.:. .:..:.:..:....|....|:|||. .....|....|:...:.:||...|
Human   108 DLRLLRLRLPVRVTSSVQPLPLPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATC 172

  Fly   184 TQIYGAGEVTERMICAGFVVQGGSDACQGDTGGPLVIDGQLVGLVSWGR--GCARPNYPTVYCYV 246
            ..:| .|.:|..|:|||.|  .|.||||||:|||||..|.|.||||||.  .|.:...|.||.|:
Human   173 HGVY-PGRITSNMVCAGGV--PGQDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYTYI 234

  Fly   247 AS 248
            .:
Human   235 CN 236

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kappaTry	NP_610674.5	Tryp_SPc	25..253	CDD:214473	68/238 (29%)
		Tryp_SPc	26..256	CDD:238113	68/237 (29%)
KLK12	NP_062544.1	Tryp_SPc	21..236	CDD:214473	68/236 (29%)
		Tryp_SPc	22..236	CDD:238113	68/235 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910