DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment kappaTry and Tmprss9

DIOPT Version :9

Sequence 1:	NP_610674.5	Gene:	kappaTry / 36215	FlyBaseID:	FBgn0043471	Length:	263	Species:	Drosophila melanogaster
Sequence 2:	XP_006513905.2	Gene:	Tmprss9 / 432478	MGIID:	3612246	Length:	1342	Species:	Mus musculus

Alignment Length:	278	Identity:	89/278 - (32%)
Similarity:	132/278 - (47%)	Gaps:	57/278 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 PEG---RIINGTTVDIARHPYLVSLRYRRDNESSYMHECAGVIISEQALITSAQC--LYGLPEET 81
            |.|   ||:.|:...:...|:.|||..||..     |.|..|:::|:.|:::|.|  :||.|  .
Mouse  1078 PPGALTRIVGGSAASLGEWPWQVSLWLRRRE-----HRCGAVLVAERWLLSAAHCFDIYGDP--M 1135

  Fly    82 KLVAVAGANTRNGTDGFIYPVANWTHHPNYDPVTVDNDIGVLLLDTTLDLTLLGISSIGIR---- 142
            :..|..|....:.|:|.:..||....||.|:..|:|.|:.:|.|...:..:.|      :|
Mouse  1136 QWAAFLGTPFLSSTEGQLERVARIYRHPFYNIYTLDYDVALLELAGPVRRSRL------VRPICL 1194

  Fly   143 --PERPAVGRLATVAGWGYREEWG-----------------------PS---SYKLEQTEVPVVS 179
              |.||..|....:.|||...|.|                       |:   :.:|::..|.|:|
Mouse  1195 PGPARPPDGARCVITGWGSLREGGIHACVRRSPGGVGDTPHLHLSPDPTGSMARQLQKAAVRVLS 1259

  Fly   180 SEQCTQIYGAGEVTERMICAGFVVQGGSDACQGDTGGPLVI---DGQ--LVGLVSWGRGCARPNY 239
            .:.|.:.|.. :::.||:|||| .|||.|:|.||.||||..   .||  |.|:.|||.||.||::
Mouse  1260 EQTCRRFYPV-QISSRMLCAGF-PQGGVDSCSGDAGGPLACREPSGQWVLTGVTSWGYGCGRPHF 1322

  Fly   240 PTVYCYVASFVDWIEETI 257
            |.||..||:.:.||.:.|
Mouse  1323 PGVYTRVAAVLGWIGQNI 1340

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kappaTry	NP_610674.5	Tryp_SPc	25..253	CDD:214473	84/266 (32%)
kappaTry	NP_610674.5	Tryp_SPc	26..256	CDD:238113	85/268 (32%)
Tmprss9	XP_006513905.2	SEA	285..365	CDD:366610
		LDLa	407..442	CDD:238060
		Tryp_SPc	455..684	CDD:214473
		Tryp_SPc	756..984	CDD:214473
		Tryp_SPc	1085..1336	CDD:238113	83/265 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920