Protein Alignment kappaTry and KLK2

DIOPT Version :10

• Sequence 1: NP_610674.5
• Gene: kappaTry / 36215
• FlyBaseID: FBgn0043471
• Length: 263
• Species: Drosophila melanogaster
• Sequence 2: NP_005542.1
• Gene: KLK2 / 3817
• HGNCID: 6363
• Length: 261
• Species: Homo sapiens
• Alignment Length: 293
• Identity: 85/293 - (29%)
• Similarity: 134/293 - (45%)
• Gaps: 80/293 - (27%)

  Fly     6 LLLAIGFSSVISISGQPEGRIINGTTVDIARHPYLVSLRYRRDNESSYMH---ECAGVIISEQAL 67
            :.|::|.:..:.:.   :.||:.|...:....|:.|::         |.|   .|.||::..|.:
Human     8 IALSVGCTGAVPLI---QSRIVGGWECEKHSQPWQVAV---------YSHGWAHCGGVLVHPQWV 60

  Fly    68 ITSAQCL----------YGL--PEETKLVAVAGANTRNGTDGFIYPVANWTHHPNYDPVTVDNDI 120
            :|:|.||          :.|  ||:|               |...||::...||.|:
Human    61 LTAAHCLKKNSQVWLGRHNLFEPEDT---------------GQRVPVSHSFPHPLYN-------- 102

  Fly   121 GVLLL---------DTTLDLTLLGISS----------IGIRPERPAVGRLATVAGWGYREEWGPS 166
             :.||         |::.||.||.:|.          :|:..:.||:|.....:|||..|   |.
Human   103 -MSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIE---PE 163

  Fly   167 SY----KLEQTEVPVVSSEQCTQIYGAGEVTERMICAGFVVQGGSDACQGDTGGPLVIDGQLVGL 227
            .:    .|:...:.::|::.|.:.| :.:|||.|:||| :..||.|.|.||:|||||.:|.|.|:
Human   164 EFLRPRSLQCVSLHLLSNDMCARAY-SEKVTEFMLCAG-LWTGGKDTCGGDSGGPLVCNGVLQGI 226

  Fly   228 VSWG-RGCARPNYPTVYCYVASFVDWIEETIAA 259
            .||| ..||.|..|.||..|..:..||::||||
Human   227 TSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAA 259

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kappaTry	NP_610674.5	Tryp_SPc	26..256	CDD:238113	78/268 (29%)
KLK2	NP_005542.1	Tryp_SPc	25..256	CDD:238113	78/268 (29%)