Protein Alignment kappaTry and KLK1

DIOPT Version :10

• Sequence 1: NP_610674.5
• Gene: kappaTry / 36215
• FlyBaseID: FBgn0043471
• Length: 263
• Species: Drosophila melanogaster
• Sequence 2: NP_002248.1
• Gene: KLK1 / 3816
• HGNCID: 6357
• Length: 262
• Species: Homo sapiens
• Alignment Length: 284
• Identity: 75/284 - (26%)
• Similarity: 133/284 - (46%)
• Gaps: 56/284 - (19%)

  Fly     1 MCIPLLLLAIGFSSVISISGQPEGRIINGTTVDIARHPYLVSLRYRRDNESSYMHECAGVIISEQ 65
            :|:.|.|...|.:..|      :.||:.|...:....|:..:|.:    .|::  :|.|:::..|
Human     6 LCLALSLGGTGAAPPI------QSRIVGGWECEQHSQPWQAALYH----FSTF--QCGGILVHRQ 58

  Fly    66 ALITSAQCL----------YGLPEETKLVAVAGANTRNGTDGFIYPVANWTHHPNYDPVTVDN-- 118
            .::|:|.|:          :.|.::            ..|..|:: |:....||.::...::|
Human    59 WVLTAAHCISDNYQLWLGRHNLFDD------------ENTAQFVH-VSESFPHPGFNMSLLENHT 110

  Fly   119 ---------DIGVLLLDTTLDLTLLGISSIGIRPERPAVGRLATVAGWGYREEWGPSSYK----L 170
                     |:.:|.|....|.....:..:.:..|.|.||.....:|||..|   |.::.    |
Human   111 RQADEDYSHDLMLLRLTEPADTITDAVKVVELPTEEPEVGSTCLASGWGSIE---PENFSFPDDL 172

  Fly   171 EQTEVPVVSSEQCTQIYGAGEVTERMICAGFVVQGGSDACQGDTGGPLVIDGQLVGLVSWGR-GC 234
            :..::.::.:::|.:.: ..:||:.|:|.|. ::||.|.|.||:||||:.||.|.|:.|||. .|
Human   173 QCVDLKILPNDECKKAH-VQKVTDFMLCVGH-LEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPC 235

  Fly   235 ARPNYPTVYCYVASFVDWIEETIA 258
            ..||.|:|...|.|:|.|||:|||
Human   236 GTPNKPSVAVRVLSYVKWIEDTIA 259

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kappaTry	NP_610674.5	Tryp_SPc	26..256	CDD:238113	66/255 (26%)
KLK1	NP_002248.1	Tryp_SPc	25..257	CDD:238113	66/255 (26%)