Protein Alignment kappaTry and KLK3

DIOPT Version :10

• Sequence 1: NP_610674.5
• Gene: kappaTry / 36215
• FlyBaseID: FBgn0043471
• Length: 263
• Species: Drosophila melanogaster
• Sequence 2: NP_001639.1
• Gene: KLK3 / 354
• HGNCID: 6364
• Length: 261
• Species: Homo sapiens
• Alignment Length: 286
• Identity: 86/286 - (30%)
• Similarity: 136/286 - (47%)
• Gaps: 54/286 - (18%)

  Fly     1 MCIPLLLLAIGFSSVISISGQP--EGRIINGTTVDIARHPY--LVSLRYRRDNESSYMHECAGVI 61
            |.:|::.|.:   ||..|...|  ..||:.|...:....|:  ||:.|.|.        .|.||:
Human     1 MWVPVVFLTL---SVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRA--------VCGGVL 54

  Fly    62 ISEQALITSAQCLYGLPEETKLVAVAGANT--RNGTDGFIYPVANWTHHPNYDPVTVDN------ 118
            :..|.::|:|.|:     ..|.|.:.|.::  .....|.::.|::...||.||...:.|
Human    55 VHPQWVLTAAHCI-----RNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPG 114

  Fly   119 DIGVLLLDTTLDLTLLGISS----------IGIRPERPAVGRLATVAGWGYREEWGPSSY----K 169
            |      |::.||.||.:|.          :.:..:.||:|.....:|||..|   |..:    |
Human   115 D------DSSHDLMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIE---PEEFLTPKK 170

  Fly   170 LEQTEVPVVSSEQCTQIYGAGEVTERMICAGFVVQGGSDACQGDTGGPLVIDGQLVGLVSWG-RG 233
            |:..::.|:|::.|.|:: ..:||:.|:|||... ||...|.||:|||||.:|.|.|:.||| ..
Human   171 LQCVDLHVISNDVCAQVH-PQKVTKFMLCAGRWT-GGKSTCSGDSGGPLVCNGVLQGITSWGSEP 233

  Fly   234 CARPNYPTVYCYVASFVDWIEETIAA 259
            ||.|..|::|..|..:..||::||.|
Human   234 CALPERPSLYTKVVHYRKWIKDTIVA 259

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kappaTry	NP_610674.5	Tryp_SPc	26..256	CDD:238113	75/254 (30%)
KLK3	NP_001639.1	Tryp_SPc	25..256	CDD:238113	75/254 (30%)