DRSC/TRiP Functional Genomics Resources

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Protein Alignment kappaTry and TMPRSS7

DIOPT Version :10

Sequence 1:NP_610674.5 Gene:kappaTry / 36215 FlyBaseID:FBgn0043471 Length:263 Species:Drosophila melanogaster
Sequence 2:NP_001382436.1 Gene:TMPRSS7 / 344805 HGNCID:30846 Length:843 Species:Homo sapiens


Alignment Length:245 Identity:92/245 - (37%)
Similarity:123/245 - (50%) Gaps:22/245 - (8%)


- Green bases have known domain annotations that are detailed below.


  Fly    25 RIINGTTVDIARHPYLVSLRYRRDNESSYMHECAGVIISEQALITSAQCLYG--LPEETKLVAVA 87
            |||.||.......|:.|||.:   ..|:|   |...:||.:.|:::|.|.:|  |.:.|...|..
Human   605 RIIGGTDTLEGGWPWQVSLHF---VGSAY---CGASVISREWLLSAAHCFHGNRLSDPTPWTAHL 663

  Fly    88 GANTRNGTDGFIYPVANWTHHPNYDPVTVDNDIGVLLLDTTLDLTLLG-ISSIGIRP--ERPAVG 149
            |...: |...|:.||.....|..|:..|.|.||.:|.|......||.. |..|.|.|  :|...|
Human   664 GMYVQ-GNAKFVSPVRRIVVHEYYNSQTFDYDIALLQLSIAWPETLKQLIQPICIPPTGQRVRSG 727

  Fly   150 RLATVAGWGYREEW-GPSSYKLEQTEVPVVSSEQCTQIYGAGEVTERMICAGFVVQGGSDACQGD 213
            ....|.|||.|.|. ...|..|:|.||.::....|...||.  :|.||:||| ::.|..|||:||
Human   728 EKCWVTGWGRRHEADNKGSLVLQQAEVELIDQTLCVSTYGI--ITSRMLCAG-IMSGKRDACKGD 789

  Fly   214 TGGPLVI----DGQ--LVGLVSWGRGCARPNYPTVYCYVASFVDWIEETI 257
            :||||..    ||:  |.|:||||.|..|||:|.||..|::||.||.:.:
Human   790 SGGPLSCRRKSDGKWILTGIVSWGHGSGRPNFPGVYTRVSNFVPWIHKYV 839

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kappaTryNP_610674.5 Tryp_SPc 26..256 CDD:238113 91/241 (38%)
TMPRSS7NP_001382436.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 27..67
SEA 108..207 CDD:460188
CUB 247..359 CDD:238001
LDLa 484..518 CDD:238060
LDLa 559..594 CDD:238060
Tryp_SPc 605..835 CDD:214473 90/239 (38%)
Blue background indicates that the domain is not in the aligned region.

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