Protein Alignment kappaTry and HPN

DIOPT Version :10

• Sequence 1: NP_610674.5
• Gene: kappaTry / 36215
• FlyBaseID: FBgn0043471
• Length: 263
• Species: Drosophila melanogaster
• Sequence 2: NP_002142.1
• Gene: HPN / 3249
• HGNCID: 5155
• Length: 417
• Species: Homo sapiens
• Alignment Length: 288
• Identity: 91/288 - (31%)
• Similarity: 135/288 - (46%)
• Gaps: 62/288 - (21%)

  Fly    15 VISISGQPEG------------------RIINGTTVDIARHPYLVSLRYRRDNESSYMHECAGVI 61
            |||:...|.|                  ||:.|....:.|.|:.|||||      ...|.|.|.:
Human   134 VISVCDCPRGRFLAAICQDCGRRKLPVDRIVGGRDTSLGRWPWQVSLRY------DGAHLCGGSL 192

  Fly    62 ISEQALITSAQCLYGLPEETKLVA----VAGANTRNGTDGFIYPVANWTHHPNY----DPVTVD- 117
            :|...::|:|.|   .||..::::    .|||..:....|....|....:|..|    ||.:.:
Human   193 LSGDWVLTAAHC---FPERNRVLSRWRVFAGAVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEEN 254

  Fly   118 -NDIGVLLLDTTLDLTLLGISSIGIRPE-RPAV------GRLATVAGWGYREEWGPSSYKLEQTE 174
             |||.::.|.:.|.||..      |:|. .||.      |::.||.|||..:.:|..:..|::..
Human   255 SNDIALVHLSSPLPLTEY------IQPVCLPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEAR 313

  Fly   175 VPVVSSEQC--TQIYGAGEVTERMICAGFVVQGGSDACQGDTGGPLVIDG--------QLVGLVS 229
            ||::|::.|  ...|| .::..:|.|||: .:||.||||||:|||.|.:.        :|.|:||
Human   314 VPIISNDVCNGADFYG-NQIKPKMFCAGY-PEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVS 376

  Fly   230 WGRGCARPNYPTVYCYVASFVDWIEETI 257
            ||.|||....|.||..|:.|.:||.:.|
Human   377 WGTGCALAQKPGVYTKVSDFREWIFQAI 404

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kappaTry	NP_610674.5	Tryp_SPc	26..256	CDD:238113	84/256 (33%)
HPN	NP_002142.1	Hepsin-SRCR	51..159	CDD:462736	5/24 (21%)
		Tryp_SPc	163..400	CDD:238113	82/253 (32%)