Protein Alignment kappaTry and GZMK

DIOPT Version :10

• Sequence 1: NP_610674.5
• Gene: kappaTry / 36215
• FlyBaseID: FBgn0043471
• Length: 263
• Species: Drosophila melanogaster
• Sequence 2: NP_002095.1
• Gene: GZMK / 3003
• HGNCID: 4711
• Length: 264
• Species: Homo sapiens
• Alignment Length: 254
• Identity: 73/254 - (28%)
• Similarity: 112/254 - (44%)
• Gaps: 44/254 - (17%)

  Fly    26 IINGTTVDIARHPYLVSLRYRRDNESSYMHECAGVIISEQALITSAQCLYGLPEETKLVAVAGAN 90
            ||.|..|.....|::.|::|      ...|.|.||:|..|.::|:|.|.|...:......|.||:
Human    27 IIGGKEVSPHSRPFMASIQY------GGHHVCGGVLIDPQWVLTAAHCQYRFTKGQSPTVVLGAH 85

  Fly    91 TRNGTDG---------FIYPVANWTHHPNYDPVTVDNDIGVLLLDTTLDLT----LLGI-SSIGI 141
            :.:..:.         || |.:..|..|.      .|||.::.|.|...|.    :|.| |...:
Human    86 SLSKNEASKQTLEIKKFI-PFSRVTSDPQ------SNDIMLVKLQTAAKLNKHVKMLHIRSKTSL 143

  Fly   142 RPERPAVGRLATVAGWGYREEWGPSSYK----LEQTEVPVVSSEQC-TQIYGAGE--VTERMICA 199
            |.     |....|.|||..:   |.|.:    |.:..|.|:|.:.| :|.|..|:  :|:.|:||
Human   144 RS-----GTKCKVTGWGATD---PDSLRPSDTLREVTVTVLSRKLCNSQSYYNGDPFITKDMVCA 200

  Fly   200 GFVVQGGSDACQGDTGGPLVIDGQLVGLVSWGRGCARPNYPTVYCYVA-SFVDWIEETI 257
            | ..:|..|:|:||:||||:..|....:||.|..|.....|.:|..:. .:..||:..:
Human   201 G-DAKGQKDSCKGDSGGPLICKGVFHAIVSGGHECGVATKPGIYTLLTKKYQTWIKSNL 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kappaTry	NP_610674.5	Tryp_SPc	26..256	CDD:238113	73/251 (29%)
GZMK	NP_002095.1	Tryp_SPc	27..257	CDD:238113	73/251 (29%)