Protein Alignment kappaTry and GZMA

DIOPT Version :10

• Sequence 1: NP_610674.5
• Gene: kappaTry / 36215
• FlyBaseID: FBgn0043471
• Length: 263
• Species: Drosophila melanogaster
• Sequence 2: NP_006135.2
• Gene: GZMA / 3001
• HGNCID: 4708
• Length: 262
• Species: Homo sapiens
• Alignment Length: 268
• Identity: 79/268 - (29%)
• Similarity: 123/268 - (45%)
• Gaps: 29/268 - (10%)

  Fly     8 LAIGFSSVISISGQPEG---RIINGTTVDIARHPYLVSLRYRRDNESSYMHECAGVIISEQALIT 69
            ||...|.|:|:...||.   :||.|..|.....||:|.|...|..      .|||.:|::..::|
Human     8 LASSLSVVVSLLLIPEDVCEKIIGGNEVTPHSRPYMVLLSLDRKT------ICAGALIAKDWVLT 66

  Fly    70 SAQCLYGLPEETKLVAVAGANTRNGTDGFIYPVANWTHHPNYDPVTVDNDIGVLLLDTTLDL--- 131
            :|.|  .|.:.::::..|.:.||......|..|.....:|.|||.|.:.|:.:|.|.....:
Human    67 AAHC--NLNKRSQVILGAHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKY 129

  Fly   132 -TLLGISSIG--IRPERPAVGRLATVAGWGYREEWGPSSYKLEQTEVPVVSSEQCT--QIYGAGE 191
             |:|.:...|  ::|     |.:..|||||........|..|.:..:.::..:.|.  ..|....
Human   130 VTILHLPKKGDDVKP-----GTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNHYNFNP 189

  Fly   192 VT-ERMICAGFVVQGGSDACQGDTGGPLVIDGQLVGLVSWG--RGCARPNYPTVYCYVA-SFVDW 252
            |. ..|:||| .::||.|:|.||:|.||:.:|...|:.|:|  ..|..|..|.||..:: ..::|
Human   190 VIGMNMVCAG-SLRGGRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNW 253

  Fly   253 IEETIAAA 260
            |..||..|
Human   254 IIMTIKGA 261

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kappaTry	NP_610674.5	Tryp_SPc	26..256	CDD:238113	69/241 (29%)
GZMA	NP_006135.2	Tryp_SPc	29..254	CDD:238113	67/238 (28%)