DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment kappaTry and Tmprss5

DIOPT Version :9

Sequence 1:	NP_610674.5	Gene:	kappaTry / 36215	FlyBaseID:	FBgn0043471	Length:	263	Species:	Drosophila melanogaster
Sequence 2:	NP_695223.2	Gene:	Tmprss5 / 266681	RGDID:	628625	Length:	445	Species:	Rattus norvegicus

Alignment Length:	252	Identity:	83/252 - (32%)
Similarity:	124/252 - (49%)	Gaps:	35/252 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 RIINGTTVDIARHPYLVSLRYRRDNESSYMHECAGVIISEQALITSAQCLYGL--------PEET 81
            ||:.|..|...|.|:..|:..      ...|.|...:::...::|:|.|:|..        ....
  Rat   207 RIVGGQAVASGRWPWQASVML------GSRHTCGASVLAPYWVVTAAHCMYSFRLSRLSSWRVHA 265

  Fly    82 KLVAVAGANTRNGTDGFIYPVANWTHHPNYDPVTVDNDIGVLLLDTTLDLT-LLGISSIGIRPER 145
            .||:.:......||     .|.....||.|.....|.|:.:|.|.|.::.: .:....:..:.:.
  Rat   266 GLVSHSAVRQHQGT-----MVEKIIPHPLYSAQNHDYDVALLQLRTPINFSDTVSAVCLPAKEQH 325

  Fly   146 PAVGRLATVAGWGYREEWGP----SSYKLEQTEVPVVSSEQCTQ--IYGAGEVTERMICAGFVVQ 204
            ...|....|:|||:.:   |    ||..|:.|.||::|::.|..  :| :|.:|.||:|||: :.
  Rat   326 FPQGSQCWVSGWGHTD---PSHTHSSDTLQDTMVPLLSTDLCNSSCMY-SGALTHRMLCAGY-LD 385

  Fly   205 GGSDACQGDTGGPLVIDG----QLVGLVSWGRGCARPNYPTVYCYVASFVDWIEETI 257
            |.:||||||:|||||...    .|||:||||||||.||.|.||..||.|:|||.:|:
  Rat   386 GRADACQGDSGGPLVCPSGDTWHLVGVVSWGRGCAEPNRPGVYAKVAEFLDWIHDTV 442

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kappaTry	NP_610674.5	Tryp_SPc	25..253	CDD:214473	80/246 (33%)
kappaTry	NP_610674.5	Tryp_SPc	26..256	CDD:238113	81/248 (33%)
Tmprss5	NP_695223.2	SRCR_2	106..203	CDD:406055
Tmprss5	NP_695223.2	Tryp_SPc	208..441	CDD:238113	81/248 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920