DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment kappaTry and St14

DIOPT Version :9

Sequence 1:	NP_610674.5	Gene:	kappaTry / 36215	FlyBaseID:	FBgn0043471	Length:	263	Species:	Drosophila melanogaster
Sequence 2:	XP_036010597.1	Gene:	St14 / 19143	MGIID:	1338881	Length:	875	Species:	Mus musculus

Alignment Length:	254	Identity:	77/254 - (30%)
Similarity:	125/254 - (49%)	Gaps:	35/254 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 EGRIINGTTVDIARHPYLVSLRYRRDNESSYMHECAGVIISEQALITSAQCL-----YGLPEETK 82
            :.|::.||..|....|:.|||     :.....|.|...:||...|:::|.|.     :...:.|.
Mouse   632 QARVVGGTNADEGEWPWQVSL-----HALGQGHLCGASLISPDWLVSAAHCFQDDKNFKYSDYTM 691

  Fly    83 LVAVAG---ANTRNGTDGFIYPVANWTHHPNYDPVTVDNDIGVLLLDTTLDLTLLGISSIGIRP- 143
            ..|..|   .:.|:.:......:.....||:::..|.|.||.:|.|:.:::.:.:      :||
Mouse   692 WTAFLGLLDQSKRSASGVQELKLKRIITHPSFNDFTFDYDIALLELEKSVEYSTV------VRPI 750

  Fly   144 -------ERPAVGRLATVAGWGYREEWGPSSYKLEQTEVPVVSSEQCTQIYGAGEVTERMICAGF 201
                   ..|| |:...|.|||:.:|.|..:..|::.|:.|::...|..:. ..::|.||:|.||
Mouse   751 CLPDATHVFPA-GKAIWVTGWGHTKEGGTGALILQKGEIRVINQTTCEDLM-PQQITPRMMCVGF 813

  Fly   202 VVQGGSDACQGDTGGPLVI---DGQL--VGLVSWGRGCARPNYPTVYCYVASFVDWIEE 255
             :.||.|:||||:||||..   ||::  .|:||||.|||:.|.|.||..:....|||:|
Mouse   814 -LSGGVDSCQGDSGGPLSSAEKDGRMFQAGVVSWGEGCAQRNKPGVYTRLPVVRDWIKE 871

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kappaTry	NP_610674.5	Tryp_SPc	25..253	CDD:214473	74/248 (30%)
kappaTry	NP_610674.5	Tryp_SPc	26..256	CDD:238113	76/251 (30%)
St14	XP_036010597.1	SEA	108..198	CDD:396113
		CUB	247..352	CDD:238001
		CUB	360..464	CDD:238001
		LDLa	474..506	CDD:238060
		LDLa	512..543	CDD:238060
		LDLa	545..579	CDD:238060
		LDLa	587..622	CDD:238060
		Tryp_SPc	635..872	CDD:238113	76/251 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920