Protein Alignment kappaTry and CFD

DIOPT Version :10

• Sequence 1: NP_610674.5
• Gene: kappaTry / 36215
• FlyBaseID: FBgn0043471
• Length: 263
• Species: Drosophila melanogaster
• Sequence 2: NP_001304264.1
• Gene: CFD / 1675
• HGNCID: 2771
• Length: 260
• Species: Homo sapiens
• Alignment Length: 248
• Identity: 79/248 - (31%)
• Similarity: 124/248 - (50%)
• Gaps: 27/248 - (10%)

  Fly    22 PEGRIINGTTVDIARHPYLVSLRYRRDNESSYMHECAGVIISEQALITSAQCLYGLPEETKLVAV 86
            |.|||:.|...:....||:.|:      :.:..|.|.||:::||.::::|.||.. ..:.|:..:
Human    29 PRGRILGGREAEAHARPYMASV------QLNGAHLCGGVLVAEQWVLSAAHCLED-AADGKVQVL 86

  Fly    87 AGANTRNGTDGF--IYPVANWTHHPNYDPVTVDNDIGVLLLDTTLDLTLLGISSIGIRP------ 143
            .||::.:..:..  :|.|.....||:..|.|:|:|:  |||..:...||    ...:||
Human    87 LGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDL--LLLQLSEKATL----GPAVRPLPWQRV 145

  Fly   144 ERP-AVGRLATVAGWGYREEWGPSSYKLEQTEVPVVSSEQCT-QIYGAGEVTERMICAGFVVQGG 206
            :|. |.|.|..|||||.....|.....|:...:||:....|. :.:..|.:|||::||   ....
Human   146 DRDVAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNRRTHHDGAITERLMCA---ESNR 207

  Fly   207 SDACQGDTGGPLVIDGQLVGLVSWG-RGCARPNYPTVYCYVASFVDWIEETIA 258
            .|:|:||:|||||..|.|.|:|:.| |.|.....|.:|..|||:..||:..:|
Human   208 RDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTRVASYAAWIDSVLA 260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kappaTry	NP_610674.5	Tryp_SPc	26..256	CDD:238113	75/240 (31%)
CFD	NP_001304264.1	Tryp_SPc	33..258	CDD:238113	75/240 (31%)