Protein Alignment kappaTry and CTRB1

DIOPT Version :10

• Sequence 1: NP_610674.5
• Gene: kappaTry / 36215
• FlyBaseID: FBgn0043471
• Length: 263
• Species: Drosophila melanogaster
• Sequence 2: NP_001897.4
• Gene: CTRB1 / 1504
• HGNCID: 2521
• Length: 263
• Species: Homo sapiens
• Alignment Length: 278
• Identity: 89/278 - (32%)
• Similarity: 130/278 - (46%)
• Gaps: 44/278 - (15%)

  Fly     2 CIPLLLLAIGFSSVISISGQPE--------GRIINGTTVDIARHPYLVSLRYRRDNESSYMHECA 58
            |..|:..|.|       .|.|.        .||:||........|:.|||:     :.:..|.|.
Human     9 CFSLVGAAFG-------CGVPAIHPVLSGLSRIVNGEDAVPGSWPWQVSLQ-----DKTGFHFCG 61

  Fly    59 GVIISEQALITSAQCLYGLPEETKLVAVAGANTRNGTDG---FIYPVANWTHHPNYDPVTVDNDI 120
            |.:|||..::|:|.|  |:  .|..|.||| ....|:|.   .:..:|....:|.:..:||:|||
Human    62 GSLISEDWVVTAAHC--GV--RTSDVVVAG-EFDQGSDEENIQVLKIAKVFKNPKFSILTVNNDI 121

  Fly   121 GVLLLDT--TLDLTLLGISSIGIRPERPAVGRLATVAGWG---YREEWGPSSYKLEQTEVPVVSS 180
            .:|.|.|  ....|:..:.......:.|| |.|....|||   |.....|.  ||:|..:|::|:
Human   122 TLLKLATPARFSQTVSAVCLPSADDDFPA-GTLCATTGWGKTKYNANKTPD--KLQQAALPLLSN 183

  Fly   181 EQCTQIYGAGEVTERMICAGFVVQGGSDACQGDTGGPLVI--DG--QLVGLVSWGRGCARPNYPT 241
            .:|.:.:|. .:|:.|||||   ..|..:|.||:|||||.  ||  .|||:||||......:.|.
Human   184 AECKKSWGR-RITDVMICAG---ASGVSSCMGDSGGPLVCQKDGAWTLVGIVSWGSDTCSTSSPG 244

  Fly   242 VYCYVASFVDWIEETIAA 259
            ||..|...:.|:::.:||
Human   245 VYARVTKLIPWVQKILAA 262

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kappaTry	NP_610674.5	Tryp_SPc	26..256	CDD:238113	80/241 (33%)
CTRB1	NP_001897.4	Tryp_SPc	34..259	CDD:238113	80/241 (33%)