DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment kappaTry and St14

DIOPT Version :9

Sequence 1:	NP_610674.5	Gene:	kappaTry / 36215	FlyBaseID:	FBgn0043471	Length:	263	Species:	Drosophila melanogaster
Sequence 2:	NP_446087.1	Gene:	St14 / 114093	RGDID:	69288	Length:	855	Species:	Rattus norvegicus

Alignment Length:	254	Identity:	77/254 - (30%)
Similarity:	126/254 - (49%)	Gaps:	35/254 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 EGRIINGTTVDIARHPYLVSLRYRRDNESSYMHECAGVIISEQALITSAQC-----LYGLPEETK 82
            :.|::.||..|....|:.|||     :.....|.|...:||...|:::|.|     ::...:.|.
  Rat   612 QARVVGGTNADEGEWPWQVSL-----HALGQGHLCGASLISPDWLVSAAHCFQDETIFKYSDHTM 671

  Fly    83 LVAVAG---ANTRNGTDGFIYPVANWTHHPNYDPVTVDNDIGVLLLDTTLDLTLLGISSIGIRP- 143
            ..|..|   .:.|:.:....:.:.....||:::..|.|.||.:|.|:...:.:.:      :||
  Rat   672 WTAFLGLLDQSKRSASGVQEHKLKRIITHPSFNDFTFDYDIALLELEKPAEYSTV------VRPI 730

  Fly   144 -------ERPAVGRLATVAGWGYREEWGPSSYKLEQTEVPVVSSEQCTQIYGAGEVTERMICAGF 201
                   ..|| |:...|.|||:.:|.|..:..|::.|:.|::...|.::. ..::|.||:|.||
  Rat   731 CLPDNTHVFPA-GKAIWVTGWGHTKEGGTGALILQKGEIRVINQTTCEELL-PQQITPRMMCVGF 793

  Fly   202 VVQGGSDACQGDTGGPLVI---DGQL--VGLVSWGRGCARPNYPTVYCYVASFVDWIEE 255
             :.||.|:||||:||||..   ||::  .|:||||.|||:.|.|.||..:....|||:|
  Rat   794 -LSGGVDSCQGDSGGPLSSVEKDGRIFQAGVVSWGEGCAQRNKPGVYTRIPEVRDWIKE 851

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kappaTry	NP_610674.5	Tryp_SPc	25..253	CDD:214473	74/248 (30%)
kappaTry	NP_610674.5	Tryp_SPc	26..256	CDD:238113	76/251 (30%)
St14	NP_446087.1	SEA	88..178	CDD:396113
		CUB	214..332	CDD:238001
		CUB	340..444	CDD:238001
		LDLa	454..486	CDD:238060
		LDLa	492..523	CDD:238060
		LDLa	525..559	CDD:238060
		LDLa	567..602	CDD:238060
		Tryp_SPc	615..852	CDD:238113	76/251 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920