Protein Alignment kappaTry and KLK8

DIOPT Version :10

• Sequence 1: NP_610674.5
• Gene: kappaTry / 36215
• FlyBaseID: FBgn0043471
• Length: 263
• Species: Drosophila melanogaster
• Sequence 2: NP_653088.1
• Gene: KLK8 / 11202
• HGNCID: 6369
• Length: 305
• Species: Homo sapiens
• Alignment Length: 214
• Identity: 70/214 - (32%)
• Similarity: 106/214 - (49%)
• Gaps: 20/214 - (9%)

  Fly    57 CAGVIISEQALITSAQCLYGLPEETKLVAVAGANTRNGTDG--FIYPVANWTHHPNYDPVTVDND 119
            |.||::....::|:|.|     ::.|.....|.::....||  ...||.....||.|:...|::.
Human   103 CGGVLVGGNWVLTAAHC-----KKPKYTVRLGDHSLQNKDGPEQEIPVVQSIPHPCYNSSDVEDH 162

  Fly   120 IGVLLLDTTLDLTLLG--ISSIGIRPERPAVGRLATVAGWGY----REEWGPSSYKLEQTEVPVV 178
            ...|:|....|...||  :..|.:.......|:..||:|||.    ||.: |.:  |...||.:.
Human   163 NHDLMLLQLRDQASLGSKVKPISLADHCTQPGQKCTVSGWGTVTSPRENF-PDT--LNCAEVKIF 224

  Fly   179 SSEQCTQIYGAGEVTERMICAGFVVQGGSDACQGDTGGPLVIDGQLVGLVSWGRG-CARPNYPTV 242
            ..::|...| .|::|:.|:|||  ...|:|.||||:|||||.||.|.|:.|||.. |.|.:.|.|
Human   225 PQKKCEDAY-PGQITDGMVCAG--SSKGADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGV 286

  Fly   243 YCYVASFVDWIEETIAAAG 261
            |..:..::|||::.|.:.|
Human   287 YTNICRYLDWIKKIIGSKG 305

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kappaTry	NP_610674.5	Tryp_SPc	26..256	CDD:238113	68/207 (33%)
KLK8	NP_653088.1	Tryp_SPc	77..297	CDD:214473	66/204 (32%)