Protein Alignment kappaTry and KLK11

DIOPT Version :10

• Sequence 1: NP_610674.5
• Gene: kappaTry / 36215
• FlyBaseID: FBgn0043471
• Length: 263
• Species: Drosophila melanogaster
• Sequence 2: XP_011524671.1
• Gene: KLK11 / 11012
• HGNCID: 6359
• Length: 307
• Species: Homo sapiens
• Alignment Length: 290
• Identity: 81/290 - (27%)
• Similarity: 127/290 - (43%)
• Gaps: 62/290 - (21%)

  Fly     5 LLLLAIGFSSVISISGQPEGRIINGTTVDIARHPYLVSLRYRRDNESSYMHECAGVIISEQALIT 69
            ||.||.|.     :.|  |.|||.|........|:..:|     .|.:.: .|...:|:.:.|:|
Human    40 LLALATGL-----VGG--ETRIIKGFECKPHSQPWQAAL-----FEKTRL-LCGATLIAPRWLLT 91

  Fly    70 SAQCL--------------------YGLPEETKLVAVAGAN----------TRNGTDGFIYPVAN 104
            :|.||                    |.|...::.:...|.:          ||..|:.|.:|..|
Human    92 AAHCLKPWVSLTSPTHVSPDLSSSNYCLSHLSRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFN 156

  Fly   105 WTHHPNYDPVTVDNDIGVLLLDTTLDLTLLGISSIGIRPERPAVGRLATVAGWGYREEWGPSS-- 167
             ...||.|.   .|||.::.:.:.:.:| ..:..:.:.......|....::|||     ..||
Human   157 -NSLPNKDH---RNDIMLVKMASPVSIT-WAVRPLTLSSRCVTAGTSCLISGWG-----STSSPQ 211

  Fly   168 ----YKLEQTEVPVVSSEQCTQIYGAGEVTERMICAGFVVQGGSDACQGDTGGPLVIDGQLVGLV 228
                :.|....:.::..::|...| .|.:|:.|:||. |.:||.|:||||:|||||.:..|.|::
Human   212 LRLPHTLRCANITIIEHQKCENAY-PGNITDTMVCAS-VQEGGKDSCQGDSGGPLVCNQSLQGII 274

  Fly   229 SWGRG-CARPNYPTVYCYVASFVDWIEETI 257
            |||:. ||....|.||..|..:||||:||:
Human   275 SWGQDPCAITRKPGVYTKVCKYVDWIQETM 304

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kappaTry	NP_610674.5	Tryp_SPc	26..256	CDD:238113	71/266 (27%)
KLK11	XP_011524671.1	Tryp_SPc	53..300	CDD:214473	70/264 (27%)