DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment kappaTry and tmprss9

DIOPT Version :9

Sequence 1:	NP_610674.5	Gene:	kappaTry / 36215	FlyBaseID:	FBgn0043471	Length:	263	Species:	Drosophila melanogaster
Sequence 2:	XP_002940084.3	Gene:	tmprss9 / 100489279	XenbaseID:	XB-GENE-993973	Length:	1151	Species:	Xenopus tropicalis

Alignment Length:	260	Identity:	89/260 - (34%)
Similarity:	135/260 - (51%)	Gaps:	32/260 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 GFSSVISISGQPEGRIINGTTVDIARHPYLVSLRYRRDNESSYMHECAGVIISEQALITSAQCLY 75
            ||:.|:     |..:|:.|:.......|:.|||..||..     |:|..|:||::.|:::|.| :
Frog   909 GFAPVL-----PFNKIVGGSGSVRGEWPWQVSLWLRRKE-----HKCGAVLISDRWLLSAAHC-F 962

  Fly    76 GLPEETKL-VAVAGANTRNGTDGFIYPVANWTHHPNYDPVTVDNDIGVLLLDTTLDLTLLGISSI 139
            .:..:.|| .|..|....||.:|.:..:.....||.|:..|:|||:.:|.|.:.|..|.|
Frog   963 DIYSDPKLWAAYLGTPFLNGVEGRVEKIFRIHKHPFYNVYTLDNDVALLELPSPLTYTNL----- 1022

  Fly   140 GIRPE-RPAV------GRLATVAGWGYREEWGPSSYKLEQTEVPVVSSEQCTQIYGAGEVTERMI 197
             |||. .|.:      |....:.|||..:|.|..|.:|::..|.:|..:.|.:.|.. :::.||:
Frog  1023 -IRPICLPDISHIFPEGTRCFITGWGSTKEGGAMSRQLQKASVSIVGDQTCKKFYPI-QISPRML 1085

  Fly   198 CAGFVVQGGSDACQGDTGGPLVI---DGQ--LVGLVSWGRGCARPNYPTVYCYVASFVDWIEETI 257
            |||| :|||.|:|.||.||||..   .|:  |.|:.|||.|||||.:|.||..:.|..:||.:.:
Frog  1086 CAGF-MQGGVDSCSGDAGGPLACREPSGRWFLAGITSWGYGCARPYFPGVYTRITSVRNWIGQNL 1149

Fly 258 257
Frog 1150 1149

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kappaTry	NP_610674.5	Tryp_SPc	25..253	CDD:214473	83/240 (35%)
kappaTry	NP_610674.5	Tryp_SPc	26..256	CDD:238113	85/242 (35%)
tmprss9	XP_002940084.3	SEA	60..156	CDD:396113
		LDLa	186..221	CDD:238060
		Tryp_SPc	234..463	CDD:214473
		Tryp_SPc	547..774	CDD:238113
		LDLa	871..906	CDD:238060
		Tryp_SPc	919..1145	CDD:238113	83/239 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433637at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920