DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lambdaTry and prss60.1

DIOPT Version :9

Sequence 1:	NP_610673.1	Gene:	lambdaTry / 36214	FlyBaseID:	FBgn0043470	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	NP_001082915.1	Gene:	prss60.1 / 799770	ZFINID:	ZDB-GENE-070424-25	Length:	387	Species:	Danio rerio

Alignment Length:	261	Identity:	89/261 - (34%)
Similarity:	128/261 - (49%)	Gaps:	40/261 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 CSLADPIYRNEEVHIPKLDGRIVGGQDTNITQYPHQISMR--YRGNHRCGGTIYRSNQIISAAHC 77
            |.||            .|:.|||||.:.....:|.|:|:.  ..|.|.|||::..|..:::||||
Zfish    25 CGLA------------PLNNRIVGGVNAFDGSWPWQVSLHSPIYGGHFCGGSLINSEWVLTAAHC 77

  Fly    78 VNTLSGPENLTIVAGSSNIWFPTGPQQELEVRE-------IIIHPKYRTLNNDYDAAILILDGDF 135
            :..:: ..:|.:..|.:.       ||.:...|       |.:||.|..|.|:.|.|:|.|....
Zfish    78 LPRIT-TSSLLVFLGKTT-------QQGVNTYEINRTVSVITVHPSYNNLTNENDIALLHLSSAV 134

  Fly   136 EFNDAVQPIELAKERP--DHDTPVTVTGWGTTSEGGTI--SDVLQEVSVNVVDNSNCKNAY--SI 194
            .|::.::|:.||.:..  .:.|...:||||....|..:  ..:|||..:.||.|..| ||.  |.
Zfish   135 TFSNYIRPVCLAAQNSVFPNGTSSWITGWGNIQLGVNLPAPGILQETMIPVVPNDQC-NALLGSG 198

  Fly   195 MLTSRMLCAGVNGGGKDACQGDSGGPLVYNNTLL----GIVSWGTGCAREKYPGVYCSVPDVLDW 255
            .:|:.|:|||:..||:|.||||||||:|....|:    ||.|||.|||....||||..|.....|
Zfish   199 SVTNNMICAGLLQGGRDTCQGDSGGPMVSKQCLVWVQSGITSWGYGCADPYSPGVYTRVSQYQSW 263

  Fly   256 L 256
            :
Zfish   264 I 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lambdaTry	NP_610673.1	Tryp_SPc	35..255	CDD:214473	84/238 (35%)
lambdaTry	NP_610673.1	Tryp_SPc	36..259	CDD:238113	84/240 (35%)
prss60.1	NP_001082915.1	Tryp_SPc	33..264	CDD:214473	84/239 (35%)
		Tryp_SPc	34..267	CDD:238113	84/240 (35%)
		Somatomedin_B	349..382	CDD:295334
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810