DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lambdaTry and tmprss4

DIOPT Version :9

Sequence 1:	NP_610673.1	Gene:	lambdaTry / 36214	FlyBaseID:	FBgn0043470	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	XP_012822151.1	Gene:	tmprss4 / 733869	XenbaseID:	XB-GENE-940762	Length:	785	Species:	Xenopus tropicalis

Alignment Length:	272	Identity:	94/272 - (34%)
Similarity:	135/272 - (49%)	Gaps:	54/272 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 VLGVGCSLADPIYRNEEVHIPKLDGRIVGGQDTNITQYPHQISMRYRGNHRCGGTIYRSNQIISA 74
            |:.:.|:.....::.|         ||:||.:::|.:||.|:|::|.|.|.|||:|..|..|:.|
Frog   535 VVSLRCAACGTGHKQE---------RIIGGSNSDILKYPWQVSLQYMGQHICGGSILNSRWILCA 590

  Fly    75 AHCVN----------TLSGPENLTIVAGSSNIWFPTGPQQELEVREIIIHPKYRTLNNDYDAAIL 129
            |||.:          ...|...||.:.|:.             |.:|.::.||.|.....|.|:|
Frog   591 AHCFDRGQRQVDRWRVQYGITTLTYLFGTF-------------VDKIFLNSKYVTDQKPNDIALL 642

  Fly   130 ILDGDFEFNDAVQPIELAKERPDHDTPVT------VTGWGTTSEGG-TISDVLQEVSVNVVDNSN 187
            .|..|...:.:|||:.|    |.:|..:.      |||||.|.||| .::..||||:::::.::.
Frog   643 QLKSDIVASASVQPVCL----PGYDNNLVVGAVLYVTGWGHTVEGGAALASQLQEVAISLISSTT 703

  Fly   188 CKNAYSIMLTSRMLCAGVNGGGKDACQGDSGGPLVYNNTL--------LGIVSWGTGCAREKYPG 244
            |...|...:...|||||...||.|.||||||||||   :|        :||||||.||.|....|
Frog   704 CNQEYGGQILDTMLCAGKIAGGADTCQGDSGGPLV---SLGQSSHWEQVGIVSWGDGCGRPNRVG 765

  Fly   245 VYCSVPDVLDWL 256
            ||..|...|:|:
Frog   766 VYTDVQSFLNWI 777

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lambdaTry	NP_610673.1	Tryp_SPc	35..255	CDD:214473	90/244 (37%)
lambdaTry	NP_610673.1	Tryp_SPc	36..259	CDD:238113	90/246 (37%)
tmprss4	XP_012822151.1	ATF7IP_BD	<110..233	CDD:293393
		PHA03193	<206..340	CDD:177555
		LDLa	402..434	CDD:238060
		SRCR_2	453..545	CDD:292133	2/9 (22%)
		SRCR	464..541	CDD:278931	1/5 (20%)
		Tryp_SPc	551..777	CDD:214473	90/245 (37%)
		Tryp_SPc	552..777	CDD:238113	89/244 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H80930
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000