DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lambdaTry and st14a

DIOPT Version :9

Sequence 1:	NP_610673.1	Gene:	lambdaTry / 36214	FlyBaseID:	FBgn0043470	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	NP_001035441.2	Gene:	st14a / 678603	ZFINID:	ZDB-GENE-030131-6496	Length:	834	Species:	Danio rerio

Alignment Length:	270	Identity:	93/270 - (34%)
Similarity:	138/270 - (51%)	Gaps:	38/270 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 CSLADPIYRNEEVHIPKLDGRIVGGQDTNITQYPHQISMRYRG-NHRCGGTIYRSNQIISAAHCV 78
            |:.....|:.         .|||||||....::|.|:|:..:. .|.|||:|.....|::|||||
Zfish   585 CNCGTKAYKK---------SRIVGGQDAFEGEFPWQVSLHIKNIAHVCGGSIINERWIVTAAHCV 640

  Fly    79 NTLSGPENLTIVAGSSNIW--FPTGPQQELE--------VREIIIHPKYRTLNNDYDAAILILDG 133
            .     :::.|.......|  | .|...:.:        ::::|.||.|.....|.|.|::.::.
Zfish   641 Q-----DDVKIKYSQPGTWEVF-LGLHSQKDKLTATKRLLKQVIPHPYYNAYTYDNDIALMEMES 699

  Fly   134 DFEFNDAVQPIEL--AKERPDHDTPVTVTGWGTTSEGGTISDVLQEVSVNVVDNSNCKNAYSIML 196
            ...|:|.::|:.|  |.:.....|.|.::|||.|.|||:.:.|||:..|.:::::.|.......:
Zfish   700 PVTFSDTIRPVCLPTATDTFPAGTSVFISGWGATREGGSGATVLQKAEVRIINSTVCNQLMGGQI 764

  Fly   197 TSRMLCAGVNGGGKDACQGDSGGPLVYNN----TLLGIVSWGTGCAREKYPGVYCSVPDVLDWLV 257
            ||||.||||..||.|||||||||||.:.:    .|.|:||||.||||...||:|.:||....|:
Zfish   765 TSRMTCAGVLSGGVDACQGDSGGPLSFPSGKRMFLAGVVSWGDGCARRNKPGIYSNVPKFRAWI- 828

  Fly   258 ETVADKESVG 267
                 ||..|
Zfish   829 -----KEKTG 833

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lambdaTry	NP_610673.1	Tryp_SPc	35..255	CDD:214473	87/236 (37%)
lambdaTry	NP_610673.1	Tryp_SPc	36..259	CDD:238113	87/239 (36%)
st14a	NP_001035441.2	SEA	77..168	CDD:279699
		CUB	219..322	CDD:238001
		CUB	329..431	CDD:238001
		LDLa	443..472	CDD:238060
		LDLa	474..508	CDD:238060
		LDLa	510..544	CDD:238060
		LDLa	550..585	CDD:238060	93/270 (34%)
		Tryp_SPc	596..828	CDD:214473	87/237 (37%)
		Tryp_SPc	597..831	CDD:238113	88/245 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810