DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lambdaTry and f9b

DIOPT Version :9

Sequence 1:	NP_610673.1	Gene:	lambdaTry / 36214	FlyBaseID:	FBgn0043470	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	NP_001035400.1	Gene:	f9b / 678552	ZFINID:	ZDB-GENE-060421-7346	Length:	507	Species:	Danio rerio

Alignment Length:	238	Identity:	83/238 - (34%)
Similarity:	118/238 - (49%)	Gaps:	21/238 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 RIVGGQDTNITQYPHQISMRYRGNH--RCGGTIYRSNQIISAAHCVNTLSGPENLTIVAGSSNIW 97
            |||||.:....:.|.|:....:.|.  .|||::.....:|:|||||....|  :..|..|..::.
Zfish   255 RIVGGDEAIPGEIPWQVVFLEKVNKIVFCGGSLLSEEWVITAAHCVEGKQG--SFFIRVGEHDVS 317

  Fly    98 FPTGPQQELEVREIIIHPKY---RTLNNDYDAAILILDGDFEFNDAVQPIELAKERPDHDTPV-- 157
            ...|.:.:..:.|..|||:|   |:|.| :|.|:|.|.......|...||.|..:  |....:
Zfish   318 KMEGTESDHGIEEYHIHPRYNSQRSLYN-HDIALLKLKKPVILFDYAVPICLGSK--DFTENLLQ 379

  Fly   158 -----TVTGWGTTSEGGTISDVLQEVSVNVVDNSNCKNAYSIMLTSRMLCAGVNGGGKDACQGDS 217
                 .|:|||....||..|:|||:|.:..||...||.:.:..::..|.|||.:...||||||||
Zfish   380 SAENSLVSGWGRLRYGGIESNVLQKVELPYVDRIKCKGSSTDSISRFMFCAGYSTVRKDACQGDS 444

  Fly   218 GGPLV--YNNT--LLGIVSWGTGCAREKYPGVYCSVPDVLDWL 256
            |||..  |.:|  |.||||||..||:|...|:|..:...:.|:
Zfish   445 GGPHATRYKDTWFLTGIVSWGEECAKEGKYGIYTRISKYMAWI 487

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lambdaTry	NP_610673.1	Tryp_SPc	35..255	CDD:214473	82/235 (35%)
lambdaTry	NP_610673.1	Tryp_SPc	36..259	CDD:238113	82/237 (35%)
f9b	NP_001035400.1	GLA	23..86	CDD:214503
		EGF_CA	88..124	CDD:238011
		FXa_inhibition	131..167	CDD:291342
		Tryp_SPc	255..487	CDD:214473	82/236 (35%)
		Tryp_SPc	256..490	CDD:238113	82/237 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910