DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lambdaTry and c1s

DIOPT Version :9

Sequence 1:	NP_610673.1	Gene:	lambdaTry / 36214	FlyBaseID:	FBgn0043470	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	XP_002941253.2	Gene:	c1s / 613055	XenbaseID:	XB-GENE-995410	Length:	691	Species:	Xenopus tropicalis

Alignment Length:	264	Identity:	84/264 - (31%)
Similarity:	123/264 - (46%)	Gaps:	40/264 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 VHIPKLDGRIVGGQDTNITQYPHQISMRYRGNHRCGGTIYRSNQIISAAHCVNTLSGPENLTIVA 91
            ||.....|||.||......|:|..|  ::......||::.....:::|||.||....|   |:..
Frog   428 VHQSDKSGRIFGGTRAKPGQFPWMI--QFTDIELGGGSLISDRWVLTAAHVVNKKIFP---TMFG 487

  Fly    92 GSSNIWFPT----GPQQELEVREIIIHPKYR-------TLNNDYDAAILILDGDFEFNDAVQPIE 145
            |... :||.    ..::.|:.::|||||.|:       ..|.|.|.|::.|....:....:.||.
Frog   488 GVMK-FFPNTNLQSQEKRLQAKKIIIHPLYQDNEDTEGQSNFDNDIALVQLTKKVKLGSCISPIC 551

  Fly   146 LAKE--RPDHDTPVTVTGWGTTSEGGTISDVLQEVSVNVVDNSNCKNA-----YSIMLTSRMLCA 203
            |.:.  .|..:...|:.|||.|.:..:..: ||..|:::.....||.|     |   .|..||||
Frog   552 LPRRGLAPVVNEVATIAGWGKTEKRESAVN-LQFASISLSSMDKCKKATGGKGY---FTPNMLCA 612

  Fly   204 GVNGGGKDACQGDSGGPLVYNNT-------LLGIVSWG-TGCAREKYPGVYCSVPDVLDWLVETV 260
            | :..|||:|.|||||||::.:.       :.|||||| ..|...   |:|..|.:.|||:.||:
Frog   613 G-SDVGKDSCNGDSGGPLMFTDPQDSSKMYMAGIVSWGPRDCGTY---GLYTKVDNYLDWIEETI 673

  Fly   261 ADKE 264
            |..|
Frog   674 AAVE 677

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lambdaTry	NP_610673.1	Tryp_SPc	35..255	CDD:214473	75/245 (31%)
lambdaTry	NP_610673.1	Tryp_SPc	36..259	CDD:238113	76/248 (31%)
c1s	XP_002941253.2	CUB	21..131	CDD:238001
		FXa_inhibition	145..173	CDD:405372
		CUB	177..288	CDD:238001
		PHA02927	301..>436	CDD:222943	2/7 (29%)
		Tryp_SPc	436..669	CDD:214473	76/246 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910