DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lambdaTry and tmprss13b

DIOPT Version :9

Sequence 1:	NP_610673.1	Gene:	lambdaTry / 36214	FlyBaseID:	FBgn0043470	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	XP_005165399.1	Gene:	tmprss13b / 564693	ZFINID:	ZDB-GENE-090309-2	Length:	475	Species:	Danio rerio

Alignment Length:	252	Identity:	91/252 - (36%)
Similarity:	127/252 - (50%)	Gaps:	42/252 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 PKLDGRIVGGQDTNITQYPHQISMRYRGNHRCGGTIYRSNQIISAAHCV-NTLSG---PENLTIV 90
            |.:..||:||.......:|.|.|:.::|.|.|||::...:.||:||||. ...||   |.|..:.
Zfish   232 PPVSSRIIGGSVAAEGHWPWQASLHFQGKHSCGGSLVAPDFIITAAHCFPKETSGSQLPSNWKVY 296

  Fly    91 AG-SSNIWFPTGPQQELEVREIIIHPKYRTLNNDYDAAILILD---GDFEFNDAVQPIEL----- 146
            .| .|.:..|:    ...|:|||:|.||.....:||.|:|.|:   .|      |:||.|
Zfish   297 IGFVSQLKLPS----PYYVKEIILHEKYNPTTKNYDIALLKLNKPASD------VEPICLPVIGQ 351

  Fly   147 ----AKERPDHDTPVTVTGWGTTSEG-GTISDVLQEVSVNVVDNSNCK--NAYSIMLTSRMLCAG 204
                ||:       ...||:|...:| .::|..|.||:|:::|:|.|.  |.|:..:|..|.|||
Zfish   352 TFPPAKQ-------CWTTGFGVIRQGSNSVSTSLMEVTVSLIDSSVCNSPNVYNGEITENMQCAG 409

  Fly   205 VNGGGKDACQGDSGGPLVYNNT-----LLGIVSWGTGCAREKYPGVYCSVPDVLDWL 256
            ...||||:|||||||||...:.     |.|:.|||.||.:...||||..|...|.|:
Zfish   410 DLRGGKDSCQGDSGGPLACKSNDGQWFLTGVTSWGEGCGQVNRPGVYSDVAKYLMWI 466

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lambdaTry	NP_610673.1	Tryp_SPc	35..255	CDD:214473	89/244 (36%)
lambdaTry	NP_610673.1	Tryp_SPc	36..259	CDD:238113	89/246 (36%)
tmprss13b	XP_005165399.1	SRCR_2	147..230	CDD:295335
		Tryp_SPc	237..466	CDD:214473	89/245 (36%)
		Tryp_SPc	238..469	CDD:238113	89/246 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.000