DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lambdaTry and tmprss9

DIOPT Version :9

Sequence 1:	NP_610673.1	Gene:	lambdaTry / 36214	FlyBaseID:	FBgn0043470	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	XP_021325244.1	Gene:	tmprss9 / 562051	ZFINID:	ZDB-GENE-050208-573	Length:	788	Species:	Danio rerio

Alignment Length:	243	Identity:	87/243 - (35%)
Similarity:	134/243 - (55%)	Gaps:	20/243 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 PKLDGRIVGGQDTNITQYPHQISMRYRGNHRCGGTIYRSNQIISAAHCVNTLSGPENLTIVAGSS 94
            |.:..|||||::|...::|.|:|:|.||.|.||.:|..|..::|||||....:.|::.|.:.|::
Zfish   226 PVMSNRIVGGENTRHGEFPWQVSLRLRGRHTCGASIVNSRWLVSAAHCFEVENNPKDWTALVGAN 290

  Fly    95 NIWFPTGPQQE---LEVREIIIHPKYRTLNNDYDAAILILDGDFEFNDAVQPIELAKERPDH-DT 155
            .:   :|.:.|   :.::.:::.|||..:..|.|..:|.|:...:|:..|||:.:...  .| .|
Zfish   291 QV---SGAEAEAFIVNIKSLVMSPKYDPMTTDSDVTVLELETPLKFSHYVQPVCIPSS--SHVFT 350

  Fly   156 P---VTVTGWGTTSEGGT-ISDVLQEVSVNVVDNSNC--KNAYSIMLTSRMLCAGVNGGGKDACQ 214
            |   ..|:|||..::..| :...||:..|.::|:..|  .:.|...||..|:|||...|..|:||
Zfish   351 PGQNCIVSGWGALNQYTTEVPSTLQKAIVKIIDSKVCNKSSVYRGALTQNMMCAGFLQGKVDSCQ 415

  Fly   215 GDSGGPLVYNNT-----LLGIVSWGTGCAREKYPGVYCSVPDVLDWLV 257
            |||||||.....     |.||||||.|||:...||||..|..:.:|:|
Zfish   416 GDSGGPLACEVAAGRYFLAGIVSWGVGCAQINKPGVYSRVTKLRNWIV 463

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lambdaTry	NP_610673.1	Tryp_SPc	35..255	CDD:214473	84/234 (36%)
lambdaTry	NP_610673.1	Tryp_SPc	36..259	CDD:238113	85/237 (36%)
tmprss9	XP_021325244.1	SEA	52..146	CDD:307516
		LDLa	185..220	CDD:238060
		Tryp_SPc	232..462	CDD:238113	83/234 (35%)
		LDLa	510..544	CDD:238060
		Tryp_SPc	557..783	CDD:238113
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810