DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lambdaTry and tmprss13a

DIOPT Version :9

Sequence 1:	NP_610673.1	Gene:	lambdaTry / 36214	FlyBaseID:	FBgn0043470	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	NP_001152984.1	Gene:	tmprss13a / 559754	ZFINID:	ZDB-GENE-090309-3	Length:	506	Species:	Danio rerio

Alignment Length:	242	Identity:	94/242 - (38%)
Similarity:	133/242 - (54%)	Gaps:	32/242 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 RIVGGQDTNITQYPHQISMRYRGNHRCGGTIYRSNQIISAAHCVNTLSGPENLTIVAGSSN--IW 97
            ||:||..:.:.|||.|:|:.|...|.||||:...:.|:|||||   ..|.     :|.|:.  ::
Zfish   268 RIIGGTTSELGQYPWQVSLHYNKAHVCGGTLISPDFIVSAAHC---FQGK-----MANSAYWLVY 324

  Fly    98 FPTGPQQELE----VREIIIHPKYRTLNNDYDAAILILDGDFEFNDAVQPIELAKERPDHDTPVT 158
            .....||.|.    |::||:..||.:..||.|.|:|||.....|:...||:.|    |..:...:
Zfish   325 VGIVSQQSLGMPYLVKKIIVSEKYNSDTNDNDVALLILSRPVAFSYTTQPVCL----PTFNQTFS 385

  Fly   159 ------VTGWGTTSEGG-TISDVLQEVSVNVVDNSNCKNA--YSIMLTSRMLCAGVNGGGKDACQ 214
                  .:|:|||.:|. ..|..|..||||::|:|.|.:.  |..::|:.|:|||...||:|:||
Zfish   386 GGLQCWTSGFGTTKQGADRASSSLMSVSVNIIDSSVCNSCQIYCGLITNNMICAGDLKGGRDSCQ 450

  Fly   215 GDSGGPLVY---NNT--LLGIVSWGTGCAREKYPGVYCSVPDVLDWL 256
            ||||||||.   ||.  |:||.|||.||.:::.||||..|...|.|:
Zfish   451 GDSGGPLVCKDDNNRWYLVGITSWGAGCGQKQKPGVYSRVTSFLPWI 497

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lambdaTry	NP_610673.1	Tryp_SPc	35..255	CDD:214473	93/239 (39%)
lambdaTry	NP_610673.1	Tryp_SPc	36..259	CDD:238113	93/241 (39%)
tmprss13a	NP_001152984.1	SRCR_2	178..261	CDD:295335
		Tryp_SPc	268..497	CDD:214473	93/240 (39%)
		Tryp_SPc	269..497	CDD:238113	92/239 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910