DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lambdaTry and zgc:154142

DIOPT Version :9

Sequence 1:	NP_610673.1	Gene:	lambdaTry / 36214	FlyBaseID:	FBgn0043470	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	NP_001092710.1	Gene:	zgc:154142 / 555481	ZFINID:	ZDB-GENE-070615-2	Length:	1090	Species:	Danio rerio

Alignment Length:	265	Identity:	76/265 - (28%)
Similarity:	121/265 - (45%)	Gaps:	34/265 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 PKLDGRIVGGQDTNITQYPHQISMRYRGN-------HRCGGTIYRSNQIISAAHC-VNTLSGPEN 86
            |.::.|||.|:..|...:|.|:||:...:       |.||||:...|.:::|||| :........
Zfish   581 PAVNTRIVNGEPANPHSWPWQVSMQVLRDSEPPMLGHTCGGTLIHKNWVLTAAHCFIRYADELHR 645

  Fly    87 LTIVAGSSNIWFPTGPQQELEVREIIIHP--KYRTLNN-DYDAAILILDGDFEFNDAVQPIELA- 147
            ..:..|..|:......:|...|..|..|.  :|.|:.. ::|.|::.|||:.   .|.:.|:.|
Zfish   646 WKMCLGKHNLTVSESTEQCFNVLGIYRHEGFQYPTVPTVEFDIALVRLDGEV---TATEHIDFAC 707

  Fly   148 ----KERPDHDTPVTVTGWGTTSEGGT---ISDVLQEVSVNVVDNSNCK--NAYSIMLTSRMLCA 203
                :|..........||||..:...|   :::.|.:|::.||....||  :.:...:.:.|:|.
Zfish   708 LPSFEELLPGGKKCYATGWGDETGNSTAPKVAETLNQVALPVVPYETCKRMDYWWFQVKTSMICC 772

  Fly   204 GVNGGG--KDACQGDSGGPLVYNNT------LLGIVSWG-TGCAREKYPGVYCSVPDVLDWLVET 259
            |.....  |..||||||||||..::      :.||.|:| .||..:|.|.|:......|.| :|.
Zfish   773 GYTSPDELKSVCQGDSGGPLVCQDSPSAPWEVHGITSFGPIGCVFDKKPSVFTRSSVYLPW-IEN 836

  Fly   260 VADKE 264
            |..|:
Zfish   837 VIRKD 841

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lambdaTry	NP_610673.1	Tryp_SPc	35..255	CDD:214473	71/249 (29%)
lambdaTry	NP_610673.1	Tryp_SPc	36..259	CDD:238113	71/252 (28%)
zgc:154142	NP_001092710.1	CUB	57..159	CDD:238001
		CUB	172..280	CDD:238001
		CUB	310..420	CDD:238001
		CUB	432..546	CDD:238001
		Tryp_SPc	586..834	CDD:214473	72/251 (29%)
		Tryp_SPc	587..837	CDD:238113	72/253 (28%)
		CUB	850..959	CDD:238001
		CUB	971..1080	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900