DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lambdaTry and f10

DIOPT Version :9

Sequence 1:	NP_610673.1	Gene:	lambdaTry / 36214	FlyBaseID:	FBgn0043470	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	NP_001015728.1	Gene:	f10 / 548445	XenbaseID:	XB-GENE-971433	Length:	464	Species:	Xenopus tropicalis

Alignment Length:	234	Identity:	82/234 - (35%)
Similarity:	119/234 - (50%)	Gaps:	17/234 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 RIVGGQDTNITQYPHQ---ISMRYRGNHRCGGTIYRSNQIISAAHCVNTLSGPENLTIVAGSSNI 96
            |||||::.:..:.|.|   :|....|  .|||||.....|::||||:|.   .:...:|.|..|.
Frog   227 RIVGGRECSQGECPWQALLVSDEDEG--FCGGTILSREFILTAAHCMNQ---TKYFKVVVGELNT 286

  Fly    97 WFPTGPQQELEVREIIIHPKYRTLNNDYDAAILILDGDFEFNDAVQPI-----ELAKERPDHDTP 156
            ....|.:...:|.:||:||::.....|||.|::.|.....|.:.:.|.     |.|.:...::..
Frog   287 KISEGTESIHKVEKIIMHPRFVKSTYDYDIAVIKLKEAINFTENIIPACIPDPEFADQVLMNEPD 351

  Fly   157 VTVTGWGTTSEGGTISDVLQEVSVNVVDNSNCKNAYSIMLTSRMLCAGVNGGGKDACQGDSGGPL 221
            ..|:|:|...|.|..:..||.:.|..:...:||.:.:..:|..|.|||.:...|||||||||||.
Frog   352 AMVSGFGRIHERGRQASTLQMLQVPYIKRHSCKESSTFAITENMFCAGFDTEVKDACQGDSGGPH 416

  Fly   222 V--YNNT--LLGIVSWGTGCAREKYPGVYCSVPDVLDWL 256
            |  :..|  :.||||||.||||:...|||..|..:..||
Frog   417 VTPFKGTYFVTGIVSWGEGCARKGKFGVYTKVSKLHRWL 455

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lambdaTry	NP_610673.1	Tryp_SPc	35..255	CDD:214473	80/231 (35%)
lambdaTry	NP_610673.1	Tryp_SPc	36..259	CDD:238113	81/233 (35%)
f10	NP_001015728.1	GLA	22..84	CDD:214503
		EGF_CA	85..121	CDD:238011
		FXa_inhibition	128..163	CDD:373209
		Tryp_SPc	228..456	CDD:238113	81/233 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.000