DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lambdaTry and prss60.2

DIOPT Version :9

Sequence 1:	NP_610673.1	Gene:	lambdaTry / 36214	FlyBaseID:	FBgn0043470	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	NP_001099071.1	Gene:	prss60.2 / 541408	ZFINID:	ZDB-GENE-050320-109	Length:	328	Species:	Danio rerio

Alignment Length:	249	Identity:	91/249 - (36%)
Similarity:	128/249 - (51%)	Gaps:	22/249 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 LDGRIVGGQDTNITQYPHQISM---RYRGNHRCGGTIYRSNQIISAAHCVNTLSGPENLTIVAGS 93
            |:.|||||.:.....:|.|:|:   || |.|.|||::..|..:::||||:..:| ..:|.:..|.
Zfish    30 LNSRIVGGVNAPEGSWPWQVSLQSPRY-GGHFCGGSLISSEWVLTAAHCLPGVS-ESSLVVYLGR 92

  Fly    94 SNIWFPTGPQQELEVREIIIHPKYRTLNNDYDAAILILDGDFEFNDAVQPIELAKERPDHD--TP 156
            .........:....|.:||:|..|.:..||.|.|:|.|.....|||.::|:.||.:...:.  |.
Zfish    93 RTQQGVNTHETSRNVAKIIVHSSYNSNTNDNDIALLRLSSAVTFNDYIRPVCLAAQNSVYSAGTS 157

  Fly   157 VTVTGWGTTSEGGTI--SDVLQEVSVNVVDNSNCKNAY--SIMLTSRMLCAGVNGGGKDACQGDS 217
            ..:||||....|..:  ..:|||..:.||.|..| ||.  |..:|:.|:|||:..||||.|||||
Zfish   158 SWITGWGDVQAGVNLPAPGILQETMIPVVANDRC-NAQLGSGTVTNNMICAGLAKGGKDTCQGDS 221

  Fly   218 GGPLVYNNTLL-------GIVSWGTGCAREKYPGVYCSVPDVLDWLVETVADKE 264
            |||:|   |.|       ||.|||.|||....||||..|.....|:...::..:
Zfish   222 GGPMV---TRLCTVWIQAGITSWGYGCADPNSPGVYTRVSQYQSWISSKISQNQ 272

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lambdaTry	NP_610673.1	Tryp_SPc	35..255	CDD:214473	89/235 (38%)
lambdaTry	NP_610673.1	Tryp_SPc	36..259	CDD:238113	89/238 (37%)
prss60.2	NP_001099071.1	Tryp_SPc	33..264	CDD:214473	89/236 (38%)
		Tryp_SPc	34..267	CDD:238113	89/238 (37%)
		Somatomedin_B	296..326	CDD:295334
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810