DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment lambdaTry and Prss36

DIOPT Version :9

Sequence 1:	NP_610673.1	Gene:	lambdaTry / 36214	FlyBaseID:	FBgn0043470	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	XP_038942639.1	Gene:	Prss36 / 497040	RGDID:	1593186	Length:	874	Species:	Rattus norvegicus

Alignment Length:	261	Identity:	87/261 - (33%)
Similarity:	125/261 - (47%)	Gaps:	33/261 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 PKLDGRIVGGQDTNITQYPHQISMRYRGNHRCGGTIYRSNQIISAAHCV---NTLSGPENLTIVA 91
            |:...|||||.|.:...:|.|:|:.:.|.|.|||::...:.::|||||.   .||...:..:::.
  Rat    53 PEPSSRIVGGSDAHPGTWPWQVSLHHGGGHICGGSLIAPSWVLSAAHCFVTNGTLEPADEWSVLL 117

  Fly    92 GSSNIWFPTGPQQELEVRE---IIIHPKYRTLNNDYDAAILILDGDFEFNDAVQPIEL--AKERP 151
            |   :....||.:...:|.   |::...|..:....|.|:|.|....:...:|:|:.|  |....
  Rat   118 G---VHSQDGPLEGAHMRSVATILVPDNYSRVELGADLALLRLASPAKLGPSVKPVCLPRASHLF 179

  Fly   152 DHDTPVTVTGWGTTSEGGTISD------VLQEVSVNVVDNSNCKNAYS--------IMLTSRMLC 202
            .|.|....||||...|    ||      |||||.:.::..:.|:..||        :.|...|||
  Rat   180 AHGTACWATGWGDVQE----SDPLPVPWVLQEVELKLLGETACQCLYSRPGPFNLTLQLLPGMLC 240

  Fly   203 AGVNGGGKDACQGDSGGPLVYNN----TLLGIVSWGTGCAREKYPGVYCSVPDVLDWLVETVADK 263
            ||...|.:|.||||||||||..:    .|.||.|:|.||.|...|||:.:|.....|:.|.|...
  Rat   241 AGYPEGRRDTCQGDSGGPLVCEDGGRWFLAGITSFGFGCGRRNRPGVFTAVAHYESWIREHVMGS 305

  Fly   264 E 264
            |
  Rat   306 E 306

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lambdaTry	NP_610673.1	Tryp_SPc	35..255	CDD:214473	82/245 (33%)
lambdaTry	NP_610673.1	Tryp_SPc	36..259	CDD:238113	82/248 (33%)
Prss36	XP_038942639.1	Tryp_SPc	59..301	CDD:238113	82/248 (33%)
		Tryp_SPc	338..532	CDD:419748
		Tryp_SPc	607..802	CDD:419748
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166343296
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	1	1.100	-	-	O	PTHR24276
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.840