DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lambdaTry and prss27

DIOPT Version :9

Sequence 1:	NP_610673.1	Gene:	lambdaTry / 36214	FlyBaseID:	FBgn0043470	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	XP_031749235.1	Gene:	prss27 / 496619	XenbaseID:	XB-GENE-5744470	Length:	724	Species:	Xenopus tropicalis

Alignment Length:	254	Identity:	95/254 - (37%)
Similarity:	137/254 - (53%)	Gaps:	17/254 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 IPKLDGRIVGGQDTNITQYPHQISMRYRGNHRCGGTIYRSNQIISAAHCVNTLSGPENLTIVAGS 93
            ||.:..||:|||.....|:|.|:|.|..|.|.||||:.....:||||||..:.|...::|.|.|:
Frog    27 IPLVSSRIMGGQSAQEGQWPWQVSFRNNGGHFCGGTLISKQYVISAAHCFPSSSSASSVTAVLGA 91

  Fly    94 SNIWFPTGPQQELEVREIIIHPKYRTLNNDYDAAILILDGDFEFNDAVQPIELAKERPDHDTPVT 158
            ..|..|.|.|..:.|:....:|.|....:..|.:::.|.....|.:.:.|:.|..:.....|.:.
Frog    92 YMIDQPDGNQVAIPVQSATNYPSYVNEGDSGDISLVQLASPVTFTNYILPVCLPADTVTFPTGLQ 156

  Fly   159 --VTGWGT-TSEGGTISDV-LQEVSVNVVDNSNCK------NAY---SIMLTSRMLCAGVNGGGK 210
              |||||. .|:...:|.: ||||:|.::|.:.|.      |:|   ||.:.|.|:|||...|||
Frog   157 CWVTGWGNIASDVSLVSPMTLQEVAVPLIDANECNALYQTPNSYGTSSISVHSDMICAGFINGGK 221

  Fly   211 DACQGDSGGPLVYNNT----LLGIVSWGTGCAREKYPGVYCSVPDVLDWLVETVADKES 265
            |:||||||||||.:::    |.|:||:|.||.:...||||..:|...||:|...:|..|
Frog   222 DSCQGDSGGPLVCSSSGQWFLAGVVSFGEGCGQAYRPGVYTLMPSYTDWIVSYASDASS 280

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lambdaTry	NP_610673.1	Tryp_SPc	35..255	CDD:214473	88/236 (37%)
lambdaTry	NP_610673.1	Tryp_SPc	36..259	CDD:238113	90/239 (38%)
prss27	XP_031749235.1	Tryp_SPc	34..271	CDD:238113	88/236 (37%)
prss27	XP_031749235.1	Tryp_SPc	420..659	CDD:238113
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910