DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lambdaTry and masp2

DIOPT Version :9

Sequence 1:	NP_610673.1	Gene:	lambdaTry / 36214	FlyBaseID:	FBgn0043470	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	NP_001011037.1	Gene:	masp2 / 496446	XenbaseID:	XB-GENE-1007491	Length:	687	Species:	Xenopus tropicalis

Alignment Length:	259	Identity:	88/259 - (33%)
Similarity:	127/259 - (49%)	Gaps:	40/259 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 PKLDGRIVGGQDTNITQYPHQISMRYRGNHRCGGTIYRSNQIISAAHCVNTLSGPENLTIVAG-- 92
            |...||||||:..|:.::|.|:.:. ..|.|.||.:...|.|::|||.|.:.....::.|..|
Frog   438 PAAAGRIVGGEFANVGEFPWQVFIN-ANNERGGGALLLDNWILTAAHVVYSYDDLSSILIKMGFL 501

  Fly    93 ---SSNI---WFPTGPQQELEVREIIIHPKYRTLNNDYDAAILILDGDFEFN-DAVQPIEL-AKE 149
               .||.   |    |:      .:.||..|:..:.:.|.|::.|......: :::..|.| .||
Frog   502 STQDSNYIRGW----PE------AVFIHEGYKPGHYNNDIALIKLKNKVPLSEESILGICLPTKE 556

  Fly   150 R------PDHDTPV-TVTGWGTTSEGGTISDVLQEVSVNVVDNSNCKNAYS-----IMLTSRMLC 202
            :      .|.|..| .|.|||.| |....|..|:.|.||:||:|.||..|:     .::|..|:|
Frog   557 KSYHISHKDDDNHVGLVAGWGLT-EAQRSSRKLRFVEVNIVDHSTCKAEYAKLDAQYIVTENMIC 620

  Fly   203 AGVNGGGKDACQGDSGGPLVYNNT------LLGIVSWGTGCAREKYPGVYCSVPDVLDWLVETV 260
            ||...|.||:|.|||||.|.:.|.      :.||||||.||...:..|||..|.:.|||:.:|:
Frog   621 AGFEIGVKDSCAGDSGGALAFMNAESKKWFVGGIVSWGVGCGVARQYGVYTKVTNYLDWIEKTI 684

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lambdaTry	NP_610673.1	Tryp_SPc	35..255	CDD:214473	83/247 (34%)
lambdaTry	NP_610673.1	Tryp_SPc	36..259	CDD:238113	84/250 (34%)
masp2	NP_001011037.1	CUB	30..139	CDD:238001
		FXa_inhibition	145..180	CDD:317114
		CUB	184..294	CDD:238001
		CCP	299..361	CDD:153056
		CCP	365..430	CDD:153056
		Tryp_SPc	443..680	CDD:214473	84/248 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910