DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lambdaTry and CLIPA19

DIOPT Version :9

Sequence 1:	NP_610673.1	Gene:	lambdaTry / 36214	FlyBaseID:	FBgn0043470	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	XP_001237509.2	Gene:	CLIPA19 / 4577382	VectorBaseID:	AGAP003245	Length:	356	Species:	Anopheles gambiae

Alignment Length:	257	Identity:	65/257 - (25%)
Similarity:	111/257 - (43%)	Gaps:	35/257 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 RIVGGQDTNITQYPHQISMRYR------GNHRCGGTIYRSNQIISAAHCVNTLS----------G 83
            ::.|.|.|....||....:.|.      |.| ||||:.....|::|||||::|.          |
Mosquito   103 QLTGAQLTQPDDYPWTALIEYEKPDGTTGFH-CGGTLINQGHILTAAHCVSSLRAGWKVHRVLLG 166

  Fly    84 PENLTIVAGSS-NIWFPTGPQQELEVREIIIHPKYRTLNN--DYDAAILILDGDFEFNDAVQPI- 144
            ..:|:.|...: |:.  ..|..|.:|.:||:|..|...|.  ::|.|::..:....|.|.:.||
Mosquito   167 EWDLSSVLDCAYNVC--NNPPIEAKVSKIIVHDGYDAQNGSFNHDIALIRFEELANFPDTIVPIC 229

  Fly   145 -ELAKERPDH---DTPVTVTGWGTTSEGGTISDVLQEVSVNVVDNSNCKN--AYSIMLTSRMLCA 203
             .:|...|..   |...||.|||.:.....::..| ::::.|.:...|.:  .:...:....|||
Mosquito   230 LPIADSIPWENITDGFSTVVGWGKSQSTAGVTKKL-KLNLKVRNFRECSSLLEWPEKMQPSQLCA 293

  Fly   204 GVNGGGKDACQGDSGGPLVY----NNTLLGIV-SWGTGCAREKYPGVYCSVPDVLDWLVETV 260
            ......:..|..|:||.|.:    .:.|:|:. |....|.....|||:.:|...::|:.:.:
Mosquito   294 LWERSNRKICSADAGGGLAWFYRRFHYLIGVAGSDEQKCGSGDVPGVFVNVSYYMNWIRDNI 355

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lambdaTry	NP_610673.1	Tryp_SPc	35..255	CDD:214473	64/250 (26%)
lambdaTry	NP_610673.1	Tryp_SPc	36..259	CDD:238113	65/253 (26%)
CLIPA19	XP_001237509.2	CLIP	37..84	CDD:197829
		Tryp_SPc	106..354	CDD:238113	65/251 (26%)
		Tryp_SPc	106..351	CDD:214473	64/248 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
TreeFam	0	0.000	Not matched by this tool.
	1	1.000