DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lambdaTry and st14

DIOPT Version :9

Sequence 1:	NP_610673.1	Gene:	lambdaTry / 36214	FlyBaseID:	FBgn0043470	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	XP_012821897.2	Gene:	st14 / 448647	XenbaseID:	XB-GENE-1008784	Length:	845	Species:	Xenopus tropicalis

Alignment Length:	244	Identity:	85/244 - (34%)
Similarity:	127/244 - (52%)	Gaps:	30/244 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 RIVGGQDTNITQYPHQISMRYRGN-HRCGGTIYRSNQIISAAHCVNTLSGPENLTIVAGSSNIW- 97
            |||||.:.:..::|.|:|:..:|| |.||.::.....:||||||..     ::.::....:::|
Frog   604 RIVGGVNADTGEFPWQVSLHVKGNKHTCGASLVSPTMLISAAHCFQ-----DDQSMRYSDASLWT 663

  Fly    98 ----------FPTGPQQELEVREIIIHPKYRTLNNDYDAAILILDGDFEFNDAVQPIELAKERPD 152
                      ..:....|.:::.|:.|..:.....|.|.::|.|:...::.|.:|||.:.:...|
Frog   664 AYLGLHDQAQLNSKDVVERKIKRIMAHIGFNDNTYDNDISVLELEKPVDYTDFIQPICIPESTHD 728

  Fly   153 HDT--PVTVTGWGTTSEGGTISDVLQEVSVNVVDNSNCKNAYSIMLTSRMLCAGVNGGGKDACQG 215
            ...  |:.|||||...|||..:.:||:..:.:::.:.|.......||.||||||...||.|||||
Frog   729 FPVGKPIWVTGWGALKEGGGAAVILQKAEIRIINQTECNKLLDGQLTPRMLCAGFVSGGIDACQG 793

  Fly   216 DSGGPL--------VYNNTLLGIVSWGTGCAREKYPGVYCSVPDVLDWL 256
            ||||||        ||   |.||||||.||||...||||..|..:.||:
Frog   794 DSGGPLSSVELNNKVY---LAGIVSWGEGCARRNKPGVYTRVAMMRDWI 839

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lambdaTry	NP_610673.1	Tryp_SPc	35..255	CDD:214473	83/241 (34%)
lambdaTry	NP_610673.1	Tryp_SPc	36..259	CDD:238113	84/243 (35%)
st14	XP_012821897.2	SEA	76..167	CDD:396113
		CUB	216..320	CDD:238001
		CUB	328..432	CDD:238001
		LDLa	442..474	CDD:238060
		LDLa	476..511	CDD:238060
		LDLa	513..547	CDD:238060
		LDLa	554..587	CDD:197566
		Tryp_SPc	604..839	CDD:214473	84/242 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000